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Parkin and PINK1 mitigate STING-induced inflammation.
Sliter DA, Martinez J, Hao L, Chen X, Sun N, Fischer TD, Burman JL, Li Y, Zhang Z, Narendra DP, Cai H, Borsche M, Klein C, Youle RJ. Sliter DA, et al. Among authors: klein c. Nature. 2018 Sep;561(7722):258-262. doi: 10.1038/s41586-018-0448-9. Epub 2018 Aug 22. Nature. 2018. PMID: 30135585 Free PMC article.
Mutant Parkin impairs mitochondrial function and morphology in human fibroblasts.
Grünewald A, Voges L, Rakovic A, Kasten M, Vandebona H, Hemmelmann C, Lohmann K, Orolicki S, Ramirez A, Schapira AH, Pramstaller PP, Sue CM, Klein C. Grünewald A, et al. Among authors: klein c. PLoS One. 2010 Sep 27;5(9):e12962. doi: 10.1371/journal.pone.0012962. PLoS One. 2010. PMID: 20885945 Free PMC article.
Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neurons.
Rakovic A, Shurkewitsch K, Seibler P, Grünewald A, Zanon A, Hagenah J, Krainc D, Klein C. Rakovic A, et al. Among authors: klein c. J Biol Chem. 2013 Jan 25;288(4):2223-37. doi: 10.1074/jbc.M112.391680. Epub 2012 Dec 4. J Biol Chem. 2013. PMID: 23212910 Free PMC article.
iPS models of Parkin and PINK1.
Rakovic A, Seibler P, Klein C. Rakovic A, et al. Among authors: klein c. Biochem Soc Trans. 2015 Apr;43(2):302-7. doi: 10.1042/BST20150010. Biochem Soc Trans. 2015. PMID: 25849934 Review.
Utility and implications of exome sequencing in early-onset Parkinson's disease.
Trinh J, Lohmann K, Baumann H, Balck A, Borsche M, Brüggemann N, Dure L, Dean M, Volkmann J, Tunc S, Prasuhn J, Pawlack H, Imhoff S, Lill CM, Kasten M, Bauer P, Rolfs A; International Parkinson's Disease Genomics Consortium (IPDGC); Klein C. Trinh J, et al. Among authors: klein c. Mov Disord. 2019 Jan;34(1):133-137. doi: 10.1002/mds.27559. Epub 2018 Dec 10. Mov Disord. 2019. PMID: 30537300 Free PMC article.
3,912 results