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From hype to reality: data science enabling personalized medicine.
Fröhlich H, Balling R, Beerenwinkel N, Kohlbacher O, Kumar S, Lengauer T, Maathuis MH, Moreau Y, Murphy SA, Przytycka TM, Rebhan M, Röst H, Schuppert A, Schwab M, Spang R, Stekhoven D, Sun J, Weber A, Ziemek D, Zupan B. Fröhlich H, et al. Among authors: stekhoven d. BMC Med. 2018 Aug 27;16(1):150. doi: 10.1186/s12916-018-1122-7. BMC Med. 2018. PMID: 30145981 Free PMC article.
Causal stability ranking.
Stekhoven DJ, Moraes I, Sveinbjörnsson G, Hennig L, Maathuis MH, Bühlmann P. Stekhoven DJ, et al. Bioinformatics. 2012 Nov 1;28(21):2819-23. doi: 10.1093/bioinformatics/bts523. Epub 2012 Sep 3. Bioinformatics. 2012. PMID: 22945788
Bioinformatics for precision oncology.
Singer J, Irmisch A, Ruscheweyh HJ, Singer F, Toussaint NC, Levesque MP, Stekhoven DJ, Beerenwinkel N. Singer J, et al. Brief Bioinform. 2019 May 21;20(3):778-788. doi: 10.1093/bib/bbx143. Brief Bioinform. 2019. PMID: 29272324 Free PMC article. Review.
SwissMTB: establishing comprehensive molecular cancer diagnostics in Swiss clinics.
Singer F, Irmisch A, Toussaint NC, Grob L, Singer J, Thurnherr T, Beerenwinkel N, Levesque MP, Dummer R, Quagliata L, Rothschild SI, Wicki A, Beisel C, Stekhoven DJ. Singer F, et al. BMC Med Inform Decis Mak. 2018 Oct 29;18(1):89. doi: 10.1186/s12911-018-0680-0. BMC Med Inform Decis Mak. 2018. PMID: 30373609 Free PMC article.
The Tumor Profiler Study: integrated, multi-omic, functional tumor profiling for clinical decision support.
Irmisch A, Bonilla X, Chevrier S, Lehmann KV, Singer F, Toussaint NC, Esposito C, Mena J, Milani ES, Casanova R, Stekhoven DJ, Wegmann R, Jacob F, Sobottka B, Goetze S, Kuipers J, Sarabia Del Castillo J, Prummer M, Tuncel MA, Menzel U, Jacobs A, Engler S, Sivapatham S, Frei AL, Gut G, Ficek J, Miglino N; Tumor Profiler Consortium; Aebersold R, Bacac M, Beerenwinkel N, Beisel C, Bodenmiller B, Dummer R, Heinzelmann-Schwarz V, Koelzer VH, Manz MG, Moch H, Pelkmans L, Snijder B, Theocharides APA, Tolnay M, Wicki A, Wollscheid B, Rätsch G, Levesque MP. Irmisch A, et al. Cancer Cell. 2021 Mar 8;39(3):288-293. doi: 10.1016/j.ccell.2021.01.004. Epub 2021 Jan 21. Cancer Cell. 2021. PMID: 33482122 Free article.
scAmpi-A versatile pipeline for single-cell RNA-seq analysis from basics to clinics.
Bertolini A, Prummer M, Tuncel MA, Menzel U, Rosano-González ML, Kuipers J, Stekhoven DJ; Tumor Profiler consortium; Beerenwinkel N, Singer F. Bertolini A, et al. Among authors: stekhoven dj. PLoS Comput Biol. 2022 Jun 3;18(6):e1010097. doi: 10.1371/journal.pcbi.1010097. eCollection 2022 Jun. PLoS Comput Biol. 2022. PMID: 35658001 Free PMC article.
NGS-pipe: a flexible, easily extendable and highly configurable framework for NGS analysis.
Singer J, Ruscheweyh HJ, Hofmann AL, Thurnherr T, Singer F, Toussaint NC, Ng CKY, Piscuoglio S, Beisel C, Christofori G, Dummer R, Hall MN, Krek W, Levesque MP, Manz MG, Moch H, Papassotiropoulos A, Stekhoven DJ, Wild P, Wüst T, Rinn B, Beerenwinkel N. Singer J, et al. Bioinformatics. 2018 Jan 1;34(1):107-108. doi: 10.1093/bioinformatics/btx540. Bioinformatics. 2018. PMID: 28968639 Free PMC article.
scROSHI: robust supervised hierarchical identification of single cells.
Prummer M, Bertolini A, Bosshard L, Barkmann F, Yates J, Boeva V; Tumor Profiler Consortium; Stekhoven D, Singer F. Prummer M, et al. Among authors: stekhoven d. NAR Genom Bioinform. 2023 Jun 16;5(2):lqad058. doi: 10.1093/nargab/lqad058. eCollection 2023 Jun. NAR Genom Bioinform. 2023. PMID: 37332656 Free PMC article.
34 results