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Lipidomic profiling of patient-specific iPSC-derived hepatocyte-like cells.
Kiamehr M, Viiri LE, Vihervaara T, Koistinen KM, Hilvo M, Ekroos K, Käkelä R, Aalto-Setälä K. Kiamehr M, et al. Among authors: kakela r. Dis Model Mech. 2017 Sep 1;10(9):1141-1153. doi: 10.1242/dmm.030841. Epub 2017 Jul 21. Dis Model Mech. 2017. PMID: 28733363 Free PMC article.
Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths.
Ruuth M, Nguyen SD, Vihervaara T, Hilvo M, Laajala TD, Kondadi PK, Gisterå A, Lähteenmäki H, Kittilä T, Huusko J, Uusitupa M, Schwab U, Savolainen MJ, Sinisalo J, Lokki ML, Nieminen MS, Jula A, Perola M, Ylä-Herttula S, Rudel L, Öörni A, Baumann M, Baruch A, Laaksonen R, Ketelhuth DFJ, Aittokallio T, Jauhiainen M, Käkelä R, Borén J, Williams KJ, Kovanen PT, Öörni K. Ruuth M, et al. Among authors: kakela r. Eur Heart J. 2018 Jul 14;39(27):2562-2573. doi: 10.1093/eurheartj/ehy319. Eur Heart J. 2018. PMID: 29982602 Free PMC article.
ANGPTL3 deficiency alters the lipid profile and metabolism of cultured hepatocytes and human lipoproteins.
Ruhanen H, Haridas PAN, Minicocci I, Taskinen JH, Palmas F, di Costanzo A, D'Erasmo L, Metso J, Partanen J, Dalli J, Zhou Y, Arca M, Jauhiainen M, Käkelä R, Olkkonen VM. Ruhanen H, et al. Among authors: kakela r. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Jul;1865(7):158679. doi: 10.1016/j.bbalip.2020.158679. Epub 2020 Mar 6. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32151767
108 results