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A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers.
Mosley JD, Feng Q, Wells QS, Van Driest SL, Shaffer CM, Edwards TL, Bastarache L, Wei WQ, Davis LK, McCarty CA, Thompson W, Chute CG, Jarvik GP, Gordon AS, Palmer MR, Crosslin DR, Larson EB, Carrell DS, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Linneman JG, Namjou B, Williams MS, Ritchie MD, Borthwick KM, Verma SS, Karnes JH, Weiss ST, Wang TJ, Stein CM, Denny JC, Roden DM. Mosley JD, et al. Among authors: stein cm. Nat Commun. 2018 Aug 30;9(1):3522. doi: 10.1038/s41467-018-05624-4. Nat Commun. 2018. PMID: 30166544 Free PMC article.
Clopidogrel and the concept of high-risk pharmacokinetics.
Roden DM, Stein CM. Roden DM, et al. Among authors: stein cm. Circulation. 2009 Apr 28;119(16):2127-30. doi: 10.1161/CIRCULATIONAHA.109.865907. Circulation. 2009. PMID: 19398674 No abstract available.
Cardiovascular effects of noncardiovascular drugs.
Raj SR, Stein CM, Saavedra PJ, Roden DM. Raj SR, et al. Among authors: stein cm. Circulation. 2009 Sep 22;120(12):1123-32. doi: 10.1161/CIRCULATIONAHA.107.728576. Circulation. 2009. PMID: 19770411 Free PMC article. Review. No abstract available.
Pharmacogenomics: the genetics of variable drug responses.
Roden DM, Wilke RA, Kroemer HK, Stein CM. Roden DM, et al. Among authors: stein cm. Circulation. 2011 Apr 19;123(15):1661-70. doi: 10.1161/CIRCULATIONAHA.109.914820. Circulation. 2011. PMID: 21502584 Free PMC article. Review. No abstract available.
The use of a DNA biobank linked to electronic medical records to characterize pharmacogenomic predictors of tacrolimus dose requirement in kidney transplant recipients.
Birdwell KA, Grady B, Choi L, Xu H, Bian A, Denny JC, Jiang M, Vranic G, Basford M, Cowan JD, Richardson DM, Robinson MP, Ikizler TA, Ritchie MD, Stein CM, Haas DW. Birdwell KA, et al. Among authors: stein cm. Pharmacogenet Genomics. 2012 Jan;22(1):32-42. doi: 10.1097/FPC.0b013e32834e1641. Pharmacogenet Genomics. 2012. PMID: 22108237 Free PMC article.
506 results