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Investigation of genetic variants within candidate genes of the TNFRSF1B signalling pathway on the response to anti-TNF agents in a UK cohort of rheumatoid arthritis patients.
Bowes JD, Potter C, Gibbons LJ, Hyrich K, Plant D, Morgan AW, Wilson AG, Isaacs JD, Worthington J, Barton A; BRAGGSS. Bowes JD, et al. Among authors: worthington j. Pharmacogenet Genomics. 2009 Apr;19(4):319-23. doi: 10.1097/FPC.0b013e328328d51f. Pharmacogenet Genomics. 2009. PMID: 19262425
The role of rheumatoid arthritis genetic susceptibility markers in the prediction of erosive disease in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register.
Plant D, Thomson W, Lunt M, Flynn E, Martin P, Eyre S, Farragher T, Bunn D, Worthington J, Symmons D, Barton A. Plant D, et al. Among authors: worthington j. Rheumatology (Oxford). 2011 Jan;50(1):78-84. doi: 10.1093/rheumatology/keq032. Epub 2010 Mar 10. Rheumatology (Oxford). 2011. PMID: 20219786 Free PMC article.
Investigation of rheumatoid arthritis genetic susceptibility markers in the early rheumatoid arthritis study further replicates the TRAF1 association with radiological damage.
Viatte S, Plant D, Lunt M, Fu B, Flynn E, Parker BJ, Galloway J, Solymossy C, Worthington J, Symmons DP, Dixey JJ, Young A, Barton A. Viatte S, et al. Among authors: worthington j. J Rheumatol. 2013 Feb;40(2):144-56. doi: 10.3899/jrheum.121034. Epub 2012 Dec 15. J Rheumatol. 2013. PMID: 23242182 Free article.
Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23.
McGovern A, Schoenfelder S, Martin P, Massey J, Duffus K, Plant D, Yarwood A, Pratt AG, Anderson AE, Isaacs JD, Diboll J, Thalayasingam N, Ospelt C, Barton A, Worthington J, Fraser P, Eyre S, Orozco G. McGovern A, et al. Among authors: worthington j. Genome Biol. 2016 Nov 1;17(1):212. doi: 10.1186/s13059-016-1078-x. Genome Biol. 2016. PMID: 27799070 Free PMC article.
736 results