Graham TA - Search Results

1

The evolutionary landscape of colorectal tumorigenesis.

Cross W, Kovac M, Mustonen V, Temko D, Davis H, Baker AM, Biswas S, Arnold R, Chegwidden L, Gatenbee C, Anderson AR, Koelzer VH, Martinez P, Jiang X, Domingo E, Woodcock DJ, Feng Y, Kovacova M, Maughan T; S:CORT Consortium; Jansen M, Rodriguez-Justo M, Ashraf S, Guy R, Cunningham C, East JE, Wedge DC, Wang LM, Palles C, Heinimann K, Sottoriva A, Leedham SJ, Graham TA, Tomlinson IPM. Cross W, et al. Among authors: graham ta. Nat Ecol Evol. 2018 Oct;2(10):1661-1672. doi: 10.1038/s41559-018-0642-z. Epub 2018 Aug 31. Nat Ecol Evol. 2018. PMID: 30177804 Free PMC article.

2

Analysis of copy number changes suggests chromosomal instability in a minority of large colorectal adenomas.

Jones AM, Thirlwell C, Howarth KM, Graham T, Chambers W, Segditsas S, Page KM, Phillips RK, Thomas HJ, Sieber OM, Sawyer EJ, Tomlinson IP. Jones AM, et al. J Pathol. 2007 Nov;213(3):249-56. doi: 10.1002/path.2234. J Pathol. 2007. PMID: 17893889

3

A comprehensive genetic profile of phyllodes tumours of the breast detects important mutations, intra-tumoral genetic heterogeneity and new genetic changes on recurrence.

Jones AM, Mitter R, Springall R, Graham T, Winter E, Gillett C, Hanby AM, Tomlinson IP, Sawyer EJ; Phyllodes Tumour Consortium. Jones AM, et al. J Pathol. 2008 Apr;214(5):533-44. doi: 10.1002/path.2320. J Pathol. 2008. PMID: 18288784

4

Most low-level microsatellite instability in colorectal cancers can be explained without an elevated slippage rate.

Graham T, Halford S, Page KM, Tomlinson IP. Graham T, et al. J Pathol. 2008 Jun;215(2):204-10. doi: 10.1002/path.2351. J Pathol. 2008. PMID: 18442191

5

Clonality, founder mutations, and field cancerization in human ulcerative colitis-associated neoplasia.

Leedham SJ, Graham TA, Oukrif D, McDonald SA, Rodriguez-Justo M, Harrison RF, Shepherd NA, Novelli MR, Jankowski JA, Wright NA. Leedham SJ, et al. Among authors: graham ta. Gastroenterology. 2009 Feb;136(2):542-50.e6. doi: 10.1053/j.gastro.2008.10.086. Epub 2008 Nov 7. Gastroenterology. 2009. PMID: 19103203

6

Clonality assessment and clonal ordering of individual neoplastic crypts shows polyclonality of colorectal adenomas.

Thirlwell C, Will OC, Domingo E, Graham TA, McDonald SA, Oukrif D, Jeffrey R, Gorman M, Rodriguez-Justo M, Chin-Aleong J, Clark SK, Novelli MR, Jankowski JA, Wright NA, Tomlinson IP, Leedham SJ. Thirlwell C, et al. Among authors: graham ta. Gastroenterology. 2010 Apr;138(4):1441-54, 1454.e1-7. doi: 10.1053/j.gastro.2010.01.033. Epub 2010 Jan 25. Gastroenterology. 2010. PMID: 20102718

7

Breast cancer dormancy can be maintained by small numbers of micrometastases.

Willis L, Alarcón T, Elia G, Jones JL, Wright NA, Tomlinson IP, Graham TA, Page KM. Willis L, et al. Among authors: graham ta. Cancer Res. 2010 Jun 1;70(11):4310-7. doi: 10.1158/0008-5472.CAN-09-3144. Epub 2010 May 25. Cancer Res. 2010. PMID: 20501854 Free article.

8

Field defects in DNA repair: is loss of MGMT an initial event in colorectal carcinogenesis?

Graham TA, Leedham SJ. Graham TA, et al. Gut. 2010 Nov;59(11):1452-3. doi: 10.1136/gut.2010.222398. Gut. 2010. PMID: 20947878 No abstract available.

9

Use of methylation patterns to determine expansion of stem cell clones in human colon tissue.

Graham TA, Humphries A, Sanders T, Rodriguez-Justo M, Tadrous PJ, Preston SL, Novelli MR, Leedham SJ, McDonald SA, Wright NA. Graham TA, et al. Gastroenterology. 2011 Apr;140(4):1241-1250.e1-9. doi: 10.1053/j.gastro.2010.12.036. Epub 2010 Dec 28. Gastroenterology. 2011. PMID: 21192938

10

The clonal origins of dysplasia from intestinal metaplasia in the human stomach.

Gutierrez-Gonzalez L, Graham TA, Rodriguez-Justo M, Leedham SJ, Novelli MR, Gay LJ, Ventayol-Garcia T, Green A, Mitchell I, Stoker DL, Preston SL, Bamba S, Yamada E, Kishi Y, Harrison R, Jankowski JA, Wright NA, McDonald SA. Gutierrez-Gonzalez L, et al. Among authors: graham ta. Gastroenterology. 2011 Apr;140(4):1251-1260.e1-6. doi: 10.1053/j.gastro.2010.12.051. Epub 2011 Jan 9. Gastroenterology. 2011. PMID: 21223968

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