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A systems-level framework for drug discovery identifies Csf1R as an anti-epileptic drug target.
Srivastava PK, van Eyll J, Godard P, Mazzuferi M, Delahaye-Duriez A, Van Steenwinckel J, Gressens P, Danis B, Vandenplas C, Foerch P, Leclercq K, Mairet-Coello G, Cardenas A, Vanclef F, Laaniste L, Niespodziany I, Keaney J, Gasser J, Gillet G, Shkura K, Chong SA, Behmoaras J, Kadiu I, Petretto E, Kaminski RM, Johnson MR. Srivastava PK, et al. Among authors: gillet g. Nat Commun. 2018 Sep 3;9(1):3561. doi: 10.1038/s41467-018-06008-4. Nat Commun. 2018. PMID: 30177815 Free PMC article.
C9orf72 suppresses systemic and neural inflammation induced by gut bacteria.
Burberry A, Wells MF, Limone F, Couto A, Smith KS, Keaney J, Gillet G, van Gastel N, Wang JY, Pietilainen O, Qian M, Eggan P, Cantrell C, Mok J, Kadiu I, Scadden DT, Eggan K. Burberry A, et al. Among authors: gillet g. Nature. 2020 Jun;582(7810):89-94. doi: 10.1038/s41586-020-2288-7. Epub 2020 May 13. Nature. 2020. PMID: 32483373 Free PMC article.
Myeloid and lymphoid expression of C9orf72 regulates IL-17A signaling in mice.
Limone F, Couto A, Wang JY, Zhang Y, McCourt B, Huang C, Minkin A, Jani M, McNeer S, Keaney J, Gillet G, Gonzalez RL, Goodman WA, Kadiu I, Eggan K, Burberry A. Limone F, et al. Among authors: gillet g. Sci Transl Med. 2024 Jan 31;16(732):eadg7895. doi: 10.1126/scitranslmed.adg7895. Epub 2024 Jan 31. Sci Transl Med. 2024. PMID: 38295187
Nrh L11R single nucleotide polymorphism, a new prediction biomarker in breast cancer, impacts endoplasmic reticulum-dependent Ca2+ traffic and response to neoadjuvant chemotherapy.
Duong MQ, Gadet R, Treilleux I, Borel S, Nougarède A, Marcillat O, Gonzalo P, Mikaelian I, Popgeorgiev N, Rimokh R, Gillet G. Duong MQ, et al. Among authors: gillet g. Cell Death Dis. 2023 Jul 1;14(6):392. doi: 10.1038/s41419-023-05917-7. Cell Death Dis. 2023. PMID: 37391438 Free PMC article.
111 results