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A systems-level framework for drug discovery identifies Csf1R as an anti-epileptic drug target.
Srivastava PK, van Eyll J, Godard P, Mazzuferi M, Delahaye-Duriez A, Van Steenwinckel J, Gressens P, Danis B, Vandenplas C, Foerch P, Leclercq K, Mairet-Coello G, Cardenas A, Vanclef F, Laaniste L, Niespodziany I, Keaney J, Gasser J, Gillet G, Shkura K, Chong SA, Behmoaras J, Kadiu I, Petretto E, Kaminski RM, Johnson MR. Srivastava PK, et al. Among authors: van steenwinckel j, van eyll j. Nat Commun. 2018 Sep 3;9(1):3561. doi: 10.1038/s41467-018-06008-4. Nat Commun. 2018. PMID: 30177815 Free PMC article.
Inflammation-induced sensitization of the brain in term infants.
Fleiss B, Tann CJ, Degos V, Sigaut S, Van Steenwinckel J, Schang AL, Kichev A, Robertson NJ, Mallard C, Hagberg H, Gressens P. Fleiss B, et al. Among authors: van steenwinckel j. Dev Med Child Neurol. 2015 Apr;57 Suppl 3:17-28. doi: 10.1111/dmcn.12723. Dev Med Child Neurol. 2015. PMID: 25800488 Free article. Review.
Integrative genomics of microglia implicates DLG4 (PSD95) in the white matter development of preterm infants.
Krishnan ML, Van Steenwinckel J, Schang AL, Yan J, Arnadottir J, Le Charpentier T, Csaba Z, Dournaud P, Cipriani S, Auvynet C, Titomanlio L, Pansiot J, Ball G, Boardman JP, Walley AJ, Saxena A, Mirza G, Fleiss B, Edwards AD, Petretto E, Gressens P. Krishnan ML, et al. Among authors: van steenwinckel j. Nat Commun. 2017 Sep 5;8(1):428. doi: 10.1038/s41467-017-00422-w. Nat Commun. 2017. PMID: 28874660 Free PMC article.
Neuroinflammation in preterm babies and autism spectrum disorders.
Bokobza C, Van Steenwinckel J, Mani S, Mezger V, Fleiss B, Gressens P. Bokobza C, et al. Among authors: van steenwinckel j. Pediatr Res. 2019 Jan;85(2):155-165. doi: 10.1038/s41390-018-0208-4. Epub 2018 Nov 16. Pediatr Res. 2019. PMID: 30446768 Review.
Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain.
Van Steenwinckel J, Schang AL, Krishnan ML, Degos V, Delahaye-Duriez A, Bokobza C, Csaba Z, Verdonk F, Montané A, Sigaut S, Hennebert O, Lebon S, Schwendimann L, Le Charpentier T, Hassan-Abdi R, Ball G, Aljabar P, Saxena A, Holloway RK, Birchmeier W, Baud O, Rowitch D, Miron V, Chretien F, Leconte C, Besson VC, Petretto EG, Edwards AD, Hagberg H, Soussi-Yanicostas N, Fleiss B, Gressens P. Van Steenwinckel J, et al. Brain. 2019 Dec 1;142(12):3806-3833. doi: 10.1093/brain/awz319. Brain. 2019. PMID: 31665242 Free PMC article.
Microglia-Mediated Neurodegeneration in Perinatal Brain Injuries.
Fleiss B, Van Steenwinckel J, Bokobza C, K Shearer I, Ross-Munro E, Gressens P. Fleiss B, et al. Among authors: van steenwinckel j. Biomolecules. 2021 Jan 13;11(1):99. doi: 10.3390/biom11010099. Biomolecules. 2021. PMID: 33451166 Free PMC article. Review.
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