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CDK8 Selectively Promotes the Growth of Colon Cancer Metastases in the Liver by Regulating Gene Expression of TIMP3 and Matrix Metalloproteinases.
Liang J, Chen M, Hughes D, Chumanevich AA, Altilia S, Kaza V, Lim CU, Kiaris H, Mythreye K, Pena MM, Broude EV, Roninson IB. Liang J, et al. Among authors: mythreye k. Cancer Res. 2018 Dec 1;78(23):6594-6606. doi: 10.1158/0008-5472.CAN-18-1583. Epub 2018 Sep 5. Cancer Res. 2018. PMID: 30185549 Free PMC article.
Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis.
Singh P, Jenkins LM, Horst B, Alers V, Pradhan S, Kaur P, Srivastava T, Hempel N, Győrffy B, Broude EV, Lee NY, Mythreye K. Singh P, et al. Among authors: mythreye k. Cancer Res. 2018 Jun 1;78(11):2978-2989. doi: 10.1158/0008-5472.CAN-17-2316. Epub 2018 Mar 13. Cancer Res. 2018. PMID: 29535220 Free PMC article.
Mediator kinase CDK8/CDK19 drives YAP1-dependent BMP4-induced EMT in cancer.
Serrao A, Jenkins LM, Chumanevich AA, Horst B, Liang J, Gatza ML, Lee NY, Roninson IB, Broude EV, Mythreye K. Serrao A, et al. Among authors: mythreye k. Oncogene. 2018 Aug;37(35):4792-4808. doi: 10.1038/s41388-018-0316-y. Epub 2018 May 21. Oncogene. 2018. PMID: 29780169 Free PMC article.
Depletion of COPI in cancer cells: the role of reactive oxygen species in the induction of lipid accumulation, noncanonical lipophagy and apoptosis.
Gasparian A, Aksenova M, Oliver D, Levina E, Doran R, Lucius M, Piroli G, Oleinik N, Ogretmen B, Mythreye K, Frizzell N, Broude E, Wyatt MD, Shtutman M. Gasparian A, et al. Among authors: mythreye k. Mol Biol Cell. 2022 Dec 1;33(14):ar135. doi: 10.1091/mbc.E21-08-0420. Epub 2022 Oct 12. Mol Biol Cell. 2022. PMID: 36222847 Free PMC article.
Development of adaptive anoikis resistance promotes metastasis that can be overcome by CDK8/19 Mediator kinase inhibition.
Monavarian M, Page EF, Rajkarnikar R, Kumari A, Macias LQ, Massicano F, Lee NY, Sahoo S, Hempel N, Jolly MK, Ianov L, Worthey E, Singh A, Broude EV, Mythreye K. Monavarian M, et al. Among authors: mythreye k. bioRxiv [Preprint]. 2023 Dec 6:2023.12.04.569970. doi: 10.1101/2023.12.04.569970. bioRxiv. 2023. PMID: 38106208 Free PMC article. Preprint.
GPx3 supports ovarian cancer progression by manipulating the extracellular redox environment.
Worley BL, Kim YS, Mardini J, Zaman R, Leon KE, Vallur PG, Nduwumwami A, Warrick JI, Timmins PF, Kesterson JP, Phaëton R, Lee NY, Walter V, Endres L, Mythreye K, Aird KM, Hempel N. Worley BL, et al. Among authors: mythreye k. Redox Biol. 2019 Jul;25:101051. doi: 10.1016/j.redox.2018.11.009. Epub 2018 Nov 17. Redox Biol. 2019. PMID: 30509602 Free PMC article.
Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells.
Kim YS, Gupta Vallur P, Jones VM, Worley BL, Shimko S, Shin DH, Crawford LC, Chen CW, Aird KM, Abraham T, Shepherd TG, Warrick JI, Lee NY, Phaeton R, Mythreye K, Hempel N. Kim YS, et al. Among authors: mythreye k. Oncogene. 2020 Feb;39(8):1619-1633. doi: 10.1038/s41388-019-1097-7. Epub 2019 Nov 13. Oncogene. 2020. PMID: 31723239 Free PMC article.
60 results