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Mechanism of activation of protein kinase JAK2 by the growth hormone receptor.
Brooks AJ, Dai W, O'Mara ML, Abankwa D, Chhabra Y, Pelekanos RA, Gardon O, Tunny KA, Blucher KM, Morton CJ, Parker MW, Sierecki E, Gambin Y, Gomez GA, Alexandrov K, Wilson IA, Doxastakis M, Mark AE, Waters MJ. Brooks AJ, et al. Among authors: chhabra y. Science. 2014 May 16;344(6185):1249783. doi: 10.1126/science.1249783. Science. 2014. PMID: 24833397
Role of the growth hormone-IGF-1 axis in cancer.
Chhabra Y, Waters MJ, Brooks AJ. Chhabra Y, et al. Expert Rev Endocrinol Metab. 2011 Jan;6(1):71-84. doi: 10.1586/eem.10.73. Expert Rev Endocrinol Metab. 2011. PMID: 30764037
Loss of growth hormone-mediated signal transducer and activator of transcription 5 (STAT5) signaling in mice results in insulin sensitivity with obesity.
Chhabra Y, Nelson CN, Plescher M, Barclay JL, Smith AG, Andrikopoulos S, Mangiafico S, Waxman DJ, Brooks AJ, Waters MJ. Chhabra Y, et al. FASEB J. 2019 May;33(5):6412-6430. doi: 10.1096/fj.201802328R. Epub 2019 Feb 19. FASEB J. 2019. PMID: 30779881 Free PMC article.
Finally, up-regulation of IL-15 expression in muscle, with increased secretion of adiponectin and fibroblast growth factor 1 from adipose tissue, is expected to promote insulin sensitivity.-Chhabra, Y., Nelson, C. N., Plescher, M., Barclay, J. L., Smith, A. ...
Finally, up-regulation of IL-15 expression in muscle, with increased secretion of adiponectin and fibroblast growth factor 1 from adipose ti …
Growth Hormone Stops Excessive Inflammation After Partial Hepatectomy, Allowing Liver Regeneration and Survival Through Induction of H2-Bl/HLA-G.
Ishikawa M, Brooks AJ, Fernández-Rojo MA, Medina J, Chhabra Y, Minami S, Tunny KA, Parton RG, Vivian JP, Rossjohn J, Chikani V, Ramm GA, Ho KKY, Waters MJ. Ishikawa M, et al. Among authors: chhabra y. Hepatology. 2021 Feb;73(2):759-775. doi: 10.1002/hep.31297. Epub 2020 Nov 2. Hepatology. 2021. PMID: 32342533 Free PMC article.
29 results