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Cell fusion potentiates tumor heterogeneity and reveals circulating hybrid cells that correlate with stage and survival.
Gast CE, Silk AD, Zarour L, Riegler L, Burkhart JG, Gustafson KT, Parappilly MS, Roh-Johnson M, Goodman JR, Olson B, Schmidt M, Swain JR, Davies PS, Shasthri V, Iizuka S, Flynn P, Watson S, Korkola J, Courtneidge SA, Fischer JM, Jaboin J, Billingsley KG, Lopez CD, Burchard J, Gray J, Coussens LM, Sheppard BC, Wong MH. Gast CE, et al. Among authors: fischer jm. Sci Adv. 2018 Sep 12;4(9):eaat7828. doi: 10.1126/sciadv.aat7828. eCollection 2018 Sep. Sci Adv. 2018. PMID: 30214939 Free PMC article.
Relevance of circulating hybrid cells as a non-invasive biomarker for myriad solid tumors.
Dietz MS, Sutton TL, Walker BS, Gast CE, Zarour L, Sengupta SK, Swain JR, Eng J, Parappilly M, Limbach K, Sattler A, Burlingame E, Chin Y, Gower A, Mira JLM, Sapre A, Chiu YJ, Clayburgh DR, Pommier SJ, Cetnar JP, Fischer JM, Jaboin JJ, Pommier RF, Sheppard BC, Tsikitis VL, Skalet AH, Mayo SC, Lopez CD, Gray JW, Mills GB, Mitri Z, Chang YH, Chin K, Wong MH. Dietz MS, et al. Among authors: fischer jm. Sci Rep. 2021 Jul 1;11(1):13630. doi: 10.1038/s41598-021-93053-7. Sci Rep. 2021. PMID: 34211050 Free PMC article.
Hybrid Silica-Coated PLGA Nanoparticles for Enhanced Enzyme-Based Therapeutics.
Gustafson KT, Mokhtari N, Manalo EC, Montoya Mira J, Gower A, Yeh YS, Vaidyanathan M, Esener SC, Fischer JM. Gustafson KT, et al. Among authors: fischer jm. Pharmaceutics. 2022 Dec 31;15(1):143. doi: 10.3390/pharmaceutics15010143. Pharmaceutics. 2022. PMID: 36678770 Free PMC article.
Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells.
Le HH, Cinaroglu SS, Manalo EC, Ors A, Gomes MM, Duan Sahbaz B, Bonic K, Origel Marmolejo CA, Quentel A, Plaut JS, Kawashima TE, Ozdemir ES, Malhotra SV, Ahiska Y, Sezerman U, Bayram Akcapinar G, Saldivar JC, Timucin E, Fischer JM. Le HH, et al. Among authors: fischer jm. EBioMedicine. 2021 Nov;73:103646. doi: 10.1016/j.ebiom.2021.103646. Epub 2021 Oct 21. EBioMedicine. 2021. PMID: 34689087 Free PMC article.
Silica cloaking of adenovirus enhances gene delivery while reducing immunogenicity.
Sapre AA, Yong G, Yeh YS, Ruff LE, Plaut JS, Sayar Z, Agarwal A, Martinez J, Nguyen TN, Liu YT, Messmer BT, Esener SC, Fischer JM. Sapre AA, et al. Among authors: fischer jm. J Control Release. 2019 Mar 10;297:48-59. doi: 10.1016/j.jconrel.2019.01.034. Epub 2019 Jan 25. J Control Release. 2019. PMID: 30690106
92 results