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Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma.
Cell. 2018 Sep 20;175(1):101-116.e25. doi: 10.1016/j.cell.2018.08.038. Epub 2018 Sep 13.
Cell. 2018.
PMID: 30220459
Free PMC article.
Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase.
McBrayer SK, Olenchock BA, DiNatale GJ, Shi DD, Khanal J, Jennings RB, Novak JS, Oser MG, Robbins AK, Modiste R, Bonal D, Moslehi J, Bronson RT, Neuberg D, Nguyen QD, Signoretti S, Losman JA, Kaelin WG Jr.
McBrayer SK, et al. Among authors: dinatale gj.
Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3741-E3748. doi: 10.1073/pnas.1716029115. Epub 2018 Apr 2.
Proc Natl Acad Sci U S A. 2018.
PMID: 29610306
Free PMC article.
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Hsp72 Is an Intracellular Target of the α,β-Unsaturated Sesquiterpene Lactone, Parthenolide.
Shin M, McGowan A, DiNatale GJ, Chiramanewong T, Cai T, Connor RE.
Shin M, et al. Among authors: dinatale gj.
ACS Omega. 2017 Oct 31;2(10):7267-7274. doi: 10.1021/acsomega.7b00954. Epub 2017 Oct 27.
ACS Omega. 2017.
PMID: 30023543
Free PMC article.
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