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Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer.
Lord SR, Cheng WC, Liu D, Gaude E, Haider S, Metcalf T, Patel N, Teoh EJ, Gleeson F, Bradley K, Wigfield S, Zois C, McGowan DR, Ah-See ML, Thompson AM, Sharma A, Bidaut L, Pollak M, Roy PG, Karpe F, James T, English R, Adams RF, Campo L, Ayers L, Snell C, Roxanis I, Frezza C, Fenwick JD, Buffa FM, Harris AL. Lord SR, et al. Among authors: gaude e. Cell Metab. 2018 Nov 6;28(5):679-688.e4. doi: 10.1016/j.cmet.2018.08.021. Epub 2018 Sep 20. Cell Metab. 2018. PMID: 30244975 Free PMC article. Clinical Trial.
Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin.
Lord SR, Collins JM, Cheng WC, Haider S, Wigfield S, Gaude E, Fielding BA, Pinnick KE, Harjes U, Segaran A, Jha P, Hoefler G, Pollak MN, Thompson AM, Roy PG, English R, Adams RF, Frezza C, Buffa FM, Karpe F, Harris AL. Lord SR, et al. Among authors: gaude e. Br J Cancer. 2020 Jan;122(2):258-265. doi: 10.1038/s41416-019-0665-5. Epub 2019 Dec 10. Br J Cancer. 2020. PMID: 31819193 Free PMC article. Clinical Trial.
Defects in mitochondrial metabolism and cancer.
Gaude E, Frezza C. Gaude E, et al. Cancer Metab. 2014 Jul 17;2:10. doi: 10.1186/2049-3002-2-10. eCollection 2014. Cancer Metab. 2014. PMID: 25057353 Free PMC article. Review.
Mitochondrial Metabolism: Yin and Yang for Tumor Progression.
Valcarcel-Jimenez L, Gaude E, Torrano V, Frezza C, Carracedo A. Valcarcel-Jimenez L, et al. Among authors: gaude e. Trends Endocrinol Metab. 2017 Oct;28(10):748-757. doi: 10.1016/j.tem.2017.06.004. Trends Endocrinol Metab. 2017. PMID: 28938972 Free PMC article. Review.
The metabolic alterations of cancer cells.
Sciacovelli M, Gaude E, Hilvo M, Frezza C. Sciacovelli M, et al. Among authors: gaude e. Methods Enzymol. 2014;542:1-23. doi: 10.1016/B978-0-12-416618-9.00001-7. Methods Enzymol. 2014. PMID: 24862258 Review.
37 results