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One-pot, multi-component synthesis and structure-activity relationships of peptoid-based histone deacetylase (HDAC) inhibitors targeting malaria parasites.
Diedrich D, Stenzel K, Hesping E, Antonova-Koch Y, Gebru T, Duffy S, Fisher G, Schöler A, Meister S, Kurz T, Avery VM, Winzeler EA, Held J, Andrews KT, Hansen FK. Diedrich D, et al. Among authors: fisher g. Eur J Med Chem. 2018 Oct 5;158:801-813. doi: 10.1016/j.ejmech.2018.09.018. Epub 2018 Sep 7. Eur J Med Chem. 2018. PMID: 30245402 Free PMC article.
Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules.
Trenholme K, Marek L, Duffy S, Pradel G, Fisher G, Hansen FK, Skinner-Adams TS, Butterworth A, Ngwa CJ, Moecking J, Goodman CD, McFadden GI, Sumanadasa SD, Fairlie DP, Avery VM, Kurz T, Andrews KT. Trenholme K, et al. Among authors: fisher g. Antimicrob Agents Chemother. 2014 Jul;58(7):3666-78. doi: 10.1128/AAC.02721-13. Epub 2014 Apr 14. Antimicrob Agents Chemother. 2014. PMID: 24733477 Free PMC article.
Drug repurposing and human parasitic protozoan diseases.
Andrews KT, Fisher G, Skinner-Adams TS. Andrews KT, et al. Among authors: fisher g. Int J Parasitol Drugs Drug Resist. 2014 Mar 24;4(2):95-111. doi: 10.1016/j.ijpddr.2014.02.002. eCollection 2014 Aug. Int J Parasitol Drugs Drug Resist. 2014. PMID: 25057459 Free PMC article. Review.
Defining the targets of antiparasitic compounds.
Skinner-Adams TS, Sumanadasa SD, Fisher GM, Davis RA, Doolan DL, Andrews KT. Skinner-Adams TS, et al. Drug Discov Today. 2016 May;21(5):725-39. doi: 10.1016/j.drudis.2016.01.002. Epub 2016 Jan 16. Drug Discov Today. 2016. PMID: 26784142 Review.
1,402 results