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Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome.
Zhernakova DV, Le TH, Kurilshikov A, Atanasovska B, Bonder MJ, Sanna S, Claringbould A, Võsa U, Deelen P, Franke L, de Boer RA, Kuipers F, Netea MG, Hofker MH, Wijmenga C, Zhernakova A, Fu J; LifeLines cohort study; BIOS consortium. Zhernakova DV, et al. Among authors: netea mg. Nat Genet. 2018 Nov;50(11):1524-1532. doi: 10.1038/s41588-018-0224-7. Epub 2018 Sep 24. Nat Genet. 2018. PMID: 30250126 Free PMC article.
Evolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infection.
Zhernakova A, Elbers CC, Ferwerda B, Romanos J, Trynka G, Dubois PC, de Kovel CG, Franke L, Oosting M, Barisani D, Bardella MT; Finnish Celiac Disease Study Group; Joosten LA, Saavalainen P, van Heel DA, Catassi C, Netea MG, Wijmenga C. Zhernakova A, et al. Among authors: netea mg. Am J Hum Genet. 2010 Jun 11;86(6):970-7. doi: 10.1016/j.ajhg.2010.05.004. Am J Hum Genet. 2010. PMID: 20560212 Free PMC article.
Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans.
Smeekens SP, Ng A, Kumar V, Johnson MD, Plantinga TS, van Diemen C, Arts P, Verwiel ET, Gresnigt MS, Fransen K, van Sommeren S, Oosting M, Cheng SC, Joosten LA, Hoischen A, Kullberg BJ, Scott WK, Perfect JR, van der Meer JW, Wijmenga C, Netea MG, Xavier RJ. Smeekens SP, et al. Among authors: netea mg. Nat Commun. 2013;4:1342. doi: 10.1038/ncomms2343. Nat Commun. 2013. PMID: 23299892 Free PMC article.
Immunochip SNP array identifies novel genetic variants conferring susceptibility to candidaemia.
Kumar V, Cheng SC, Johnson MD, Smeekens SP, Wojtowicz A, Giamarellos-Bourboulis E, Karjalainen J, Franke L, Withoff S, Plantinga TS, van de Veerdonk FL, van der Meer JWM, Joosten LAB, Bochud PY, Marchetti O, Perfect JR, Xavier R, Kullberg BJ, Wijmenga C, Netea MG. Kumar V, et al. Among authors: netea mg. Nat Commun. 2014 Sep 8;5:4675. doi: 10.1038/ncomms5675. Nat Commun. 2014. PMID: 25197941 Free PMC article.
The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections.
Jaeger M, van der Lee R, Cheng SC, Johnson MD, Kumar V, Ng A, Plantinga TS, Smeekens SP, Oosting M, Wang X, Barchet W, Fitzgerald K, Joosten LAB, Perfect JR, Wijmenga C, van de Veerdonk FL, Huynen MA, Xavier RJ, Kullberg BJ, Netea MG. Jaeger M, et al. Among authors: netea mg. Eur J Clin Microbiol Infect Dis. 2015 May;34(5):963-974. doi: 10.1007/s10096-014-2309-2. Epub 2015 Jan 13. Eur J Clin Microbiol Infect Dis. 2015. PMID: 25579795 Free PMC article.
Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs.
Ricaño-Ponce I, Zhernakova DV, Deelen P, Luo O, Li X, Isaacs A, Karjalainen J, Di Tommaso J, Borek ZA, Zorro MM, Gutierrez-Achury J, Uitterlinden AG, Hofman A, van Meurs J; BIOS Consortium; Lifelines Cohort Study; Netea MG, Jonkers IH, Withoff S, van Duijn CM, Li Y, Ruan Y, Franke L, Wijmenga C, Kumar V. Ricaño-Ponce I, et al. Among authors: netea mg. J Autoimmun. 2016 Apr;68:62-74. doi: 10.1016/j.jaut.2016.01.002. Epub 2016 Feb 18. J Autoimmun. 2016. PMID: 26898941 Free PMC article.
Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity.
Zhernakova A, Kurilshikov A, Bonder MJ, Tigchelaar EF, Schirmer M, Vatanen T, Mujagic Z, Vila AV, Falony G, Vieira-Silva S, Wang J, Imhann F, Brandsma E, Jankipersadsing SA, Joossens M, Cenit MC, Deelen P, Swertz MA; LifeLines cohort study; Weersma RK, Feskens EJ, Netea MG, Gevers D, Jonkers D, Franke L, Aulchenko YS, Huttenhower C, Raes J, Hofker MH, Xavier RJ, Wijmenga C, Fu J. Zhernakova A, et al. Among authors: netea mg. Science. 2016 Apr 29;352(6285):565-9. doi: 10.1126/science.aad3369. Epub 2016 Apr 28. Science. 2016. PMID: 27126040 Free PMC article.
1,290 results