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Selective PPARδ Modulators Improve Mitochondrial Function: Potential Treatment for Duchenne Muscular Dystrophy (DMD).
Lagu B, Kluge AF, Tozzo E, Fredenburg R, Bell EL, Goddeeris MM, Dwyer P, Basinski A, Senaiar RS, Jaleel M, Tiwari NK, Panigrahi SK, Krishnamurthy NR, Takahashi T, Patane MA. Lagu B, et al. Among authors: takahashi t. ACS Med Chem Lett. 2018 Jul 31;9(9):935-940. doi: 10.1021/acsmedchemlett.8b00287. eCollection 2018 Sep 13. ACS Med Chem Lett. 2018. PMID: 30258544 Free PMC article.
Novel highly selective peroxisome proliferator-activated receptor δ (PPARδ) modulators with pharmacokinetic properties suitable for once-daily oral dosing.
Lagu B, Kluge AF, Fredenburg RA, Tozzo E, Senaiar RS, Jaleel M, Panigrahi SK, Tiwari NK, Krishnamurthy NR, Takahashi T, Patane MA. Lagu B, et al. Among authors: takahashi t. Bioorg Med Chem Lett. 2017 Dec 1;27(23):5230-5234. doi: 10.1016/j.bmcl.2017.10.037. Epub 2017 Oct 27. Bioorg Med Chem Lett. 2017. PMID: 29103972
Highly selective peroxisome proliferator-activated receptor δ (PPARδ) modulator demonstrates improved safety profile compared to GW501516.
Lagu B, Kluge AF, Goddeeris MM, Tozzo E, Fredenburg RA, Chellur S, Senaiar RS, Jaleel M, Babu DRK, Tiwari NK, Takahashi T, Patane MA. Lagu B, et al. Among authors: takahashi t. Bioorg Med Chem Lett. 2018 Feb 1;28(3):533-536. doi: 10.1016/j.bmcl.2017.11.006. Epub 2017 Nov 4. Bioorg Med Chem Lett. 2018. PMID: 29275935
Correction to "Selective PPARδ Modulators Improve Mitochondrial Function: Potential Treatment for Duchenne Muscular Dystrophy (DMD)".
Lagu B, Kluge AF, Tozzo E, Fredenburg R, Bell EL, Goddeeris MM, Dwyer P, Basinski A, Senaiar RS, Jaleel M, Tiwari NK, Panigrahi SK, Krishnamurthy NR, Takahashi T, Patane MA. Lagu B, et al. Among authors: takahashi t. ACS Med Chem Lett. 2019 Apr 24;10(6):1013. doi: 10.1021/acsmedchemlett.9b00160. eCollection 2019 Jun 13. ACS Med Chem Lett. 2019. PMID: 31223463 Free PMC article.
Design, Synthesis, and Structure-Activity Relationships Study of N-Pyrimidyl/Pyridyl-2-thiazolamine Analogues as Novel Positive Allosteric Modulators of M3 Muscarinic Acetylcholine Receptor.
Tanaka H, Akaiwa M, Negoro K, Kawaminami E, Mihara H, Fuji H, Okimoto R, Ino K, Ishizu K, Takahashi T. Tanaka H, et al. Among authors: takahashi t. Chem Pharm Bull (Tokyo). 2021;69(4):360-373. doi: 10.1248/cpb.c20-00877. Chem Pharm Bull (Tokyo). 2021. PMID: 33790081 Free article.
Osimertinib after Chemoradiotherapy in Stage III EGFR-Mutated NSCLC.
Lu S, Kato T, Dong X, Ahn MJ, Quang LV, Soparattanapaisarn N, Inoue T, Wang CL, Huang M, Yang JC, Cobo M, Özgüroğlu M, Casarini I, Khiem DV, Sriuranpong V, Cronemberger E, Takahashi T, Runglodvatana Y, Chen M, Huang X, Grainger E, Ghiorghiu D, van der Gronde T, Ramalingam SS; LAURA Trial Investigators. Lu S, et al. Among authors: takahashi t. N Engl J Med. 2024 Jun 2. doi: 10.1056/NEJMoa2402614. Online ahead of print. N Engl J Med. 2024. PMID: 38828946
Individuals with Methamphetamine Use Disorder Show Reduced Directed Exploration and Learning Rates Independent of an Aversive Interoceptive State Induction.
Goldman CM, Takahashi T, Lavalley CA, Li N, Taylor S, Chuning AE, Hodson R, Stewart JL, Wilson RC, Khalsa SS, Paulus MP, Smith R. Goldman CM, et al. Among authors: takahashi t. medRxiv [Preprint]. 2024 May 21:2024.05.17.24307491. doi: 10.1101/2024.05.17.24307491. medRxiv. 2024. PMID: 38826438 Free PMC article. Preprint.
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