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MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: results of a network bioinformatics approach.
Parikh VN, Jin RC, Rabello S, Gulbahce N, White K, Hale A, Cottrill KA, Shaik RS, Waxman AB, Zhang YY, Maron BA, Hartner JC, Fujiwara Y, Orkin SH, Haley KJ, Barabási AL, Loscalzo J, Chan SY. Parikh VN, et al. Among authors: chan sy. Circulation. 2012 Mar 27;125(12):1520-32. doi: 10.1161/CIRCULATIONAHA.111.060269. Epub 2012 Feb 27. Circulation. 2012. PMID: 22371328 Free PMC article.
Hypoxamirs and mitochondrial metabolism.
Cottrill KA, Chan SY, Loscalzo J. Cottrill KA, et al. Among authors: chan sy. Antioxid Redox Signal. 2014 Sep 10;21(8):1189-201. doi: 10.1089/ars.2013.5641. Epub 2014 Feb 3. Antioxid Redox Signal. 2014. PMID: 24111795 Free PMC article.
Investigating pulmonary arterial hypertension from "stem" to stern. Focus on "Identification of a common Wnt-associated genetic signature across multiple cell types in pulmonary arterial hypertension".
Cottrill KA, Chan SY. Cottrill KA, et al. Among authors: chan sy. Am J Physiol Cell Physiol. 2014 Sep 1;307(5):C413-4. doi: 10.1152/ajpcell.00242.2014. Epub 2014 Jul 16. Am J Physiol Cell Physiol. 2014. PMID: 25031019 Free PMC article. No abstract available.
Rapamycin-induced miR-21 promotes mitochondrial homeostasis and adaptation in mTORC1 activated cells.
Lam HC, Liu HJ, Baglini CV, Filippakis H, Alesi N, Nijmeh J, Du H, Lope AL, Cottrill KA, Handen A, Asara JM, Kwiatkowski DJ, Ben-Sahra I, Oldham WM, Chan SY, Henske EP. Lam HC, et al. Among authors: chan sy. Oncotarget. 2017 Aug 4;8(39):64714-64727. doi: 10.18632/oncotarget.19947. eCollection 2017 Sep 12. Oncotarget. 2017. PMID: 29029388 Free PMC article.
Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension.
Bertero T, Lu Y, Annis S, Hale A, Bhat B, Saggar R, Saggar R, Wallace WD, Ross DJ, Vargas SO, Graham BB, Kumar R, Black SM, Fratz S, Fineman JR, West JD, Haley KJ, Waxman AB, Chau BN, Cottrill KA, Chan SY. Bertero T, et al. Among authors: chan sy. J Clin Invest. 2014 Aug;124(8):3514-28. doi: 10.1172/JCI74773. Epub 2014 Jun 24. J Clin Invest. 2014. PMID: 24960162 Free PMC article.
The microRNA-130/301 family controls vasoconstriction in pulmonary hypertension.
Bertero T, Cottrill K, Krauszman A, Lu Y, Annis S, Hale A, Bhat B, Waxman AB, Chau BN, Kuebler WM, Chan SY. Bertero T, et al. Among authors: chan sy. J Biol Chem. 2015 Jan 23;290(4):2069-85. doi: 10.1074/jbc.M114.617845. Epub 2014 Dec 12. J Biol Chem. 2015. PMID: 25505270 Free PMC article.
Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit.
Bertero T, Cottrill KA, Lu Y, Haeger CM, Dieffenbach P, Annis S, Hale A, Bhat B, Kaimal V, Zhang YY, Graham BB, Kumar R, Saggar R, Saggar R, Wallace WD, Ross DJ, Black SM, Fratz S, Fineman JR, Vargas SO, Haley KJ, Waxman AB, Chau BN, Fredenburgh LE, Chan SY. Bertero T, et al. Among authors: chan sy. Cell Rep. 2015 Nov 3;13(5):1016-32. doi: 10.1016/j.celrep.2015.09.049. Epub 2015 Oct 22. Cell Rep. 2015. PMID: 26565914 Free PMC article.
1,076 results