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Page 1
XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data.
Kluin RJC, Kemper K, Kuilman T, de Ruiter JR, Iyer V, Forment JV, Cornelissen-Steijger P, de Rink I, Ter Brugge P, Song JY, Klarenbeek S, McDermott U, Jonkers J, Velds A, Adams DJ, Peeper DS, Krijgsman O. Kluin RJC, et al. Among authors: mcdermott u. BMC Bioinformatics. 2018 Oct 4;19(1):366. doi: 10.1186/s12859-018-2353-5. BMC Bioinformatics. 2018. PMID: 30286710 Free PMC article.
Inactivating CUX1 mutations promote tumorigenesis.
Wong CC, Martincorena I, Rust AG, Rashid M, Alifrangis C, Alexandrov LB, Tiffen JC, Kober C; Chronic Myeloid Disorders Working Group of the International Cancer Genome Consortium; Green AR, Massie CE, Nangalia J, Lempidaki S, Döhner H, Döhner K, Bray SJ, McDermott U, Papaemmanuil E, Campbell PJ, Adams DJ. Wong CC, et al. Among authors: mcdermott u. Nat Genet. 2014 Jan;46(1):33-8. doi: 10.1038/ng.2846. Epub 2013 Dec 8. Nat Genet. 2014. PMID: 24316979 Free PMC article.
Editorial overview: cancer genomics: kill it. Kill it dead.
Adams D, McDermott U. Adams D, et al. Among authors: mcdermott u. Curr Opin Genet Dev. 2014 Feb;24:v-vi. doi: 10.1016/j.gde.2013.12.006. Epub 2014 Feb 23. Curr Opin Genet Dev. 2014. PMID: 24569083 No abstract available.
BRAF/NRAS wild-type melanoma, NF1 status and sensitivity to trametinib.
Ranzani M, Alifrangis C, Perna D, Dutton-Regester K, Pritchard A, Wong K, Rashid M, Robles-Espinoza CD, Hayward NK, McDermott U, Garnett M, Adams DJ. Ranzani M, et al. Among authors: mcdermott u. Pigment Cell Melanoma Res. 2015 Jan;28(1):117-9. doi: 10.1111/pcmr.12316. Epub 2014 Oct 13. Pigment Cell Melanoma Res. 2015. PMID: 25243813 Free PMC article. No abstract available.
Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma.
Müller J, Krijgsman O, Tsoi J, Robert L, Hugo W, Song C, Kong X, Possik PA, Cornelissen-Steijger PD, Geukes Foppen MH, Kemper K, Goding CR, McDermott U, Blank C, Haanen J, Graeber TG, Ribas A, Lo RS, Peeper DS. Müller J, et al. Among authors: mcdermott u. Nat Commun. 2014 Dec 15;5:5712. doi: 10.1038/ncomms6712. Nat Commun. 2014. PMID: 25502142 Free PMC article.
Integration of genomic, transcriptomic and proteomic data identifies two biologically distinct subtypes of invasive lobular breast cancer.
Michaut M, Chin SF, Majewski I, Severson TM, Bismeijer T, de Koning L, Peeters JK, Schouten PC, Rueda OM, Bosma AJ, Tarrant F, Fan Y, He B, Xue Z, Mittempergher L, Kluin RJ, Heijmans J, Snel M, Pereira B, Schlicker A, Provenzano E, Ali HR, Gaber A, O'Hurley G, Lehn S, Muris JJ, Wesseling J, Kay E, Sammut SJ, Bardwell HA, Barbet AS, Bard F, Lecerf C, O'Connor DP, Vis DJ, Benes CH, McDermott U, Garnett MJ, Simon IM, Jirström K, Dubois T, Linn SC, Gallagher WM, Wessels LF, Caldas C, Bernards R. Michaut M, et al. Among authors: mcdermott u. Sci Rep. 2016 Jan 5;6:18517. doi: 10.1038/srep18517. Sci Rep. 2016. PMID: 26729235 Free PMC article.
BRAF(V600E) Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived Xenografts.
Kemper K, Krijgsman O, Kong X, Cornelissen-Steijger P, Shahrabi A, Weeber F, van der Velden DL, Bleijerveld OB, Kuilman T, Kluin RJC, Sun C, Voest EE, Ju YS, Schumacher TNM, Altelaar AFM, McDermott U, Adams DJ, Blank CU, Haanen JB, Peeper DS. Kemper K, et al. Among authors: mcdermott u. Cell Rep. 2016 Jun 28;16(1):263-277. doi: 10.1016/j.celrep.2016.05.064. Epub 2016 Jun 16. Cell Rep. 2016. PMID: 27320919 Free PMC article.
A lentiviral vector-based insertional mutagenesis screen identifies mechanisms of resistance to MAPK inhibitors in melanoma.
Ranzani M, Alifrangis C, Thompson NA, Rust AG, Allahyar A, Iyer V, Price S, Ellis P, Turner G, de Ridder J, McDermott U, Adams DJ. Ranzani M, et al. Among authors: mcdermott u. Pigment Cell Melanoma Res. 2019 Mar;32(2):332-335. doi: 10.1111/pcmr.12737. Epub 2018 Oct 19. Pigment Cell Melanoma Res. 2019. PMID: 30218636 No abstract available.
Pathway and network analysis of more than 2500 whole cancer genomes.
Reyna MA, Haan D, Paczkowska M, Verbeke LPC, Vazquez M, Kahraman A, Pulido-Tamayo S, Barenboim J, Wadi L, Dhingra P, Shrestha R, Getz G, Lawrence MS, Pedersen JS, Rubin MA, Wheeler DA, Brunak S, Izarzugaza JMG, Khurana E, Marchal K, von Mering C, Sahinalp SC, Valencia A; PCAWG Drivers and Functional Interpretation Working Group; Reimand J, Stuart JM, Raphael BJ; PCAWG Consortium. Reyna MA, et al. Nat Commun. 2020 Feb 5;11(1):729. doi: 10.1038/s41467-020-14367-0. Nat Commun. 2020. PMID: 32024854 Free PMC article.
179 results