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ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity.
Holmström TH, Moilanen AM, Ikonen T, Björkman ML, Linnanen T, Wohlfahrt G, Karlsson S, Oksala R, Korjamo T, Samajdar S, Rajagopalan S, Chelur S, Narayanan K, Ramachandra RK, Mani J, Nair R, Gowda N, Anthony T, Dhodheri S, Mukherjee S, Ujjinamatada RK, Srinivas N, Ramachandra M, Kallio PJ. Holmström TH, et al. Among authors: mani j. Mol Cancer Ther. 2019 Jan;18(1):28-38. doi: 10.1158/1535-7163.MCT-18-0204. Epub 2018 Oct 9. Mol Cancer Ther. 2019. PMID: 30301864
PD-1 derived CA-170 is an oral immune checkpoint inhibitor that exhibits preclinical anti-tumor efficacy.
Sasikumar PG, Sudarshan NS, Adurthi S, Ramachandra RK, Samiulla DS, Lakshminarasimhan A, Ramanathan A, Chandrasekhar T, Dhudashiya AA, Talapati SR, Gowda N, Palakolanu S, Mani J, Srinivasrao B, Joseph D, Kumar N, Nair R, Atreya HS, Gowda N, Ramachandra M. Sasikumar PG, et al. Among authors: mani j. Commun Biol. 2021 Jun 8;4(1):699. doi: 10.1038/s42003-021-02191-1. Commun Biol. 2021. PMID: 34103659 Free PMC article.
T cell-based targeted immunotherapies for patients with multiple myeloma.
Wang L, Jin N, Schmitt A, Greiner J, Malcherek G, Hundemer M, Mani J, Hose D, Raab MS, Ho AD, Chen BA, Goldschmidt H, Schmitt M. Wang L, et al. Among authors: mani j. Int J Cancer. 2015 Apr 15;136(8):1751-68. doi: 10.1002/ijc.29190. Epub 2014 Sep 19. Int J Cancer. 2015. PMID: 25195787 Free article. Review.
Suppression of cytomegalovirus-specific CD8(+)T cells by everolimus.
Jin N, Malcherek G, Mani J, Zurleit R, Schmitt A, Chen B, Freund M, Ho AD, Schmitt M. Jin N, et al. Among authors: mani j. Leuk Lymphoma. 2014 May;55(5):1144-50. doi: 10.3109/10428194.2013.822496. Epub 2013 Aug 31. Leuk Lymphoma. 2014. PMID: 23841510
317 results