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Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder.
de Jong S, Diniz MJA, Saloma A, Gadelha A, Santoro ML, Ota VK, Noto C; Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium; Curtis C, Newhouse SJ, Patel H, Hall LS, O Reilly PF, Belangero SI, Bressan RA, Breen G. de Jong S, et al. Commun Biol. 2018 Oct 8;1:163. doi: 10.1038/s42003-018-0155-y. eCollection 2018. Commun Biol. 2018. PMID: 30320231 Free PMC article.
Common variants at VRK2 and TCF4 conferring risk of schizophrenia.
Steinberg S, de Jong S; Irish Schizophrenia Genomics Consortium; Andreassen OA, Werge T, Børglum AD, Mors O, Mortensen PB, Gustafsson O, Costas J, Pietiläinen OP, Demontis D, Papiol S, Huttenlocher J, Mattheisen M, Breuer R, Vassos E, Giegling I, Fraser G, Walker N, Tuulio-Henriksson A, Suvisaari J, Lönnqvist J, Paunio T, Agartz I, Melle I, Djurovic S, Strengman E; GROUP; Jürgens G, Glenthøj B, Terenius L, Hougaard DM, Ørntoft T, Wiuf C, Didriksen M, Hollegaard MV, Nordentoft M, van Winkel R, Kenis G, Abramova L, Kaleda V, Arrojo M, Sanjuán J, Arango C, Sperling S, Rossner M, Ribolsi M, Magni V, Siracusano A, Christiansen C, Kiemeney LA, Veldink J, van den Berg L, Ingason A, Muglia P, Murray R, Nöthen MM, Sigurdsson E, Petursson H, Thorsteinsdottir U, Kong A, Rubino IA, De Hert M, Réthelyi JM, Bitter I, Jönsson EG, Golimbet V, Carracedo A, Ehrenreich H, Craddock N, Owen MJ, O'Donovan MC; Wellcome Trust Case Control Consortium 2; Ruggeri M, Tosato S, Peltonen L, Ophoff RA, Collier DA, St Clair D, Rietschel M, Cichon S, Stefansson H, Rujescu D, Stefansson K. Steinberg S, et al. Among authors: de jong s, de hert m. Hum Mol Genet. 2011 Oct 15;20(20):4076-81. doi: 10.1093/hmg/ddr325. Epub 2011 Jul 26. Hum Mol Genet. 2011. PMID: 21791550 Free PMC article.
Common variant at 16p11.2 conferring risk of psychosis.
Steinberg S, de Jong S, Mattheisen M, Costas J, Demontis D, Jamain S, Pietiläinen OP, Lin K, Papiol S, Huttenlocher J, Sigurdsson E, Vassos E, Giegling I, Breuer R, Fraser G, Walker N, Melle I, Djurovic S, Agartz I, Tuulio-Henriksson A, Suvisaari J, Lönnqvist J, Paunio T, Olsen L, Hansen T, Ingason A, Pirinen M, Strengman E; GROUP; Hougaard DM, Orntoft T, Didriksen M, Hollegaard MV, Nordentoft M, Abramova L, Kaleda V, Arrojo M, Sanjuán J, Arango C, Etain B, Bellivier F, Méary A, Schürhoff F, Szoke A, Ribolsi M, Magni V, Siracusano A, Sperling S, Rossner M, Christiansen C, Kiemeney LA, Franke B, van den Berg LH, Veldink J, Curran S, Bolton P, Poot M, Staal W, Rehnstrom K, Kilpinen H, Freitag CM, Meyer J, Magnusson P, Saemundsen E, Martsenkovsky I, Bikshaieva I, Martsenkovska I, Vashchenko O, Raleva M, Paketchieva K, Stefanovski B, Durmishi N, Pejovic Milovancevic M, Lecic Tosevski D, Silagadze T, Naneishvili N, Mikeladze N, Surguladze S, Vincent JB, Farmer A, Mitchell PB, Wright A, Schofield PR, Fullerton JM, Montgomery GW, Martin NG, Rubino IA, van Winkel R, Kenis G, De Hert M, Réthelyi JM, Bitter I, Terenius L, Jönsson EG, Bakker S, van Os J, Jablensky A, Leboyer M,… See abstract for full author list ➔ Steinberg S, et al. Among authors: de jong s, de hert m. Mol Psychiatry. 2014 Jan;19(1):108-14. doi: 10.1038/mp.2012.157. Epub 2012 Nov 20. Mol Psychiatry. 2014. PMID: 23164818 Free PMC article.
Immune signatures and disorder-specific patterns in a cross-disorder gene expression analysis.
de Jong S, Newhouse SJ, Patel H, Lee S, Dempster D, Curtis C, Paya-Cano J, Murphy D, Wilson CE, Horder J, Mendez MA, Asherson P, Rivera M, Costello H, Maltezos S, Whitwell S, Pitts M, Tye C, Ashwood KL, Bolton P, Curran S, McGuffin P, Dobson R, Breen G. de Jong S, et al. Br J Psychiatry. 2016 Sep;209(3):202-8. doi: 10.1192/bjp.bp.115.175471. Epub 2016 May 5. Br J Psychiatry. 2016. PMID: 27151072 Free PMC article.
Separate and combined effects of genetic variants and pre-treatment whole blood gene expression on response to exposure-based cognitive behavioural therapy for anxiety disorders.
Coleman JR, Lester KJ, Roberts S, Keers R, Lee SH, De Jong S, Gaspar H, Teismann T, Wannemüller A, Schneider S, Jöhren P, Margraf J, Breen G, Eley TC. Coleman JR, et al. Among authors: de jong s. World J Biol Psychiatry. 2017 Apr;18(3):215-226. doi: 10.1080/15622975.2016.1208841. Epub 2016 Aug 24. World J Biol Psychiatry. 2017. PMID: 27376411 Clinical Trial.
The genome-wide expression effects of escitalopram and its relationship to neurogenesis, hippocampal volume, and antidepressant response.
Powell TR, Murphy T, de Jong S, Lee SH, Tansey KE, Hodgson K, Uher R, Price J, Thuret S, Breen G. Powell TR, et al. Among authors: de jong s. Am J Med Genet B Neuropsychiatr Genet. 2017 Jun;174(4):427-434. doi: 10.1002/ajmg.b.32532. Epub 2017 Apr 10. Am J Med Genet B Neuropsychiatr Genet. 2017. PMID: 28394502 Free PMC article.
835 results