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Prefrontal Cortex-Mediated Impairments in a Genetic Model of NMDA Receptor Hypofunction Are Reversed by the Novel M1 PAM VU6004256.
Grannan MD, Mielnik CA, Moran SP, Gould RW, Ball J, Lu Z, Bubser M, Ramsey AJ, Abe M, Cho HP, Nance KD, Blobaum AL, Niswender CM, Conn PJ, Lindsley CW, Jones CK. Grannan MD, et al. Among authors: mielnik ca. ACS Chem Neurosci. 2016 Dec 21;7(12):1706-1716. doi: 10.1021/acschemneuro.6b00230. Epub 2016 Oct 5. ACS Chem Neurosci. 2016. PMID: 27617634 Free PMC article.
Postsynaptic Density-95 Isoform Abnormalities in Schizophrenia.
Funk AJ, Mielnik CA, Koene R, Newburn E, Ramsey AJ, Lipska BK, McCullumsmith RE. Funk AJ, et al. Among authors: mielnik ca. Schizophr Bull. 2017 Jul 1;43(4):891-899. doi: 10.1093/schbul/sbw173. Schizophr Bull. 2017. PMID: 28126896 Free PMC article.
Behavioral Effects of a Potential Novel TAAR1 Antagonist.
Lam VM, Mielnik CA, Baimel C, Beerepoot P, Espinoza S, Sukhanov I, Horsfall W, Gainetdinov RR, Borgland SL, Ramsey AJ, Salahpour A. Lam VM, et al. Among authors: mielnik ca. Front Pharmacol. 2018 Sep 4;9:953. doi: 10.3389/fphar.2018.00953. eCollection 2018. Front Pharmacol. 2018. PMID: 30233365 Free PMC article.
Consequences of NMDA receptor deficiency can be rescued in the adult brain.
Mielnik CA, Binko MA, Chen Y, Funk AJ, Johansson EM, Intson K, Sivananthan N, Islam R, Milenkovic M, Horsfall W, Ross RA, Groc L, Salahpour A, McCullumsmith RE, Tripathy S, Lambe EK, Ramsey AJ. Mielnik CA, et al. Mol Psychiatry. 2021 Jul;26(7):2929-2942. doi: 10.1038/s41380-020-00859-4. Epub 2020 Aug 17. Mol Psychiatry. 2021. PMID: 32807843 Free PMC article.
A novel allosteric modulator of the cannabinoid CB1 receptor ameliorates hyperdopaminergia endophenotypes in rodent models.
Mielnik CA, Sugamori KS, Finlay DB, Thorpe HHA, Schapira M, Sivananthan N, Li CK, Lam VM, Harrington S, Abdelrahman MH, Trembleau LA, McIntyre Burnham W, Khokhar JY, Salahpour A, Ramsey AJ, Glass M, Greig IR, Ross RA. Mielnik CA, et al. Neuropsychopharmacology. 2021 Jan;46(2):413-422. doi: 10.1038/s41386-020-00876-5. Epub 2020 Oct 8. Neuropsychopharmacology. 2021. PMID: 33036015 Free PMC article.
14 results