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Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers.
Papillon JPN, Nakajima K, Adair CD, Hempel J, Jouk AO, Karki RG, Mathieu S, Möbitz H, Ntaganda R, Smith T, Visser M, Hill SE, Hurtado FK, Chenail G, Bhang HC, Bric A, Xiang K, Bushold G, Gilbert T, Vattay A, Dooley J, Costa EA, Park I, Li A, Farley D, Lounkine E, Yue QK, Xie X, Zhu X, Kulathila R, King D, Hu T, Vulic K, Cantwell J, Luu C, Jagani Z. Papillon JPN, et al. Among authors: gilbert t. J Med Chem. 2018 Nov 21;61(22):10155-10172. doi: 10.1021/acs.jmedchem.8b01318. Epub 2018 Oct 31. J Med Chem. 2018. PMID: 30339381
An Isochemogenic Set of Inhibitors To Define the Therapeutic Potential of Histone Deacetylases in β-Cell Protection.
Wagner FF, Lundh M, Kaya T, McCarren P, Zhang YL, Chattopadhyay S, Gale JP, Galbo T, Fisher SL, Meier BC, Vetere A, Richardson S, Morgan NG, Christensen DP, Gilbert TJ, Hooker JM, Leroy M, Walpita D, Mandrup-Poulsen T, Wagner BK, Holson EB. Wagner FF, et al. Among authors: gilbert tj. ACS Chem Biol. 2016 Feb 19;11(2):363-74. doi: 10.1021/acschembio.5b00640. Epub 2015 Dec 7. ACS Chem Biol. 2016. PMID: 26640968
Inhibition of DYRK1A Stimulates Human β-Cell Proliferation.
Dirice E, Walpita D, Vetere A, Meier BC, Kahraman S, Hu J, Dančík V, Burns SM, Gilbert TJ, Olson DE, Clemons PA, Kulkarni RN, Wagner BK. Dirice E, et al. Diabetes. 2016 Jun;65(6):1660-71. doi: 10.2337/db15-1127. Epub 2016 Mar 7. Diabetes. 2016. PMID: 26953159 Free PMC article.
Large-scale chemical dissection of mitochondrial function.
Wagner BK, Kitami T, Gilbert TJ, Peck D, Ramanathan A, Schreiber SL, Golub TR, Mootha VK. Wagner BK, et al. Among authors: gilbert tj. Nat Biotechnol. 2008 Mar;26(3):343-51. doi: 10.1038/nbt1387. Epub 2008 Feb 24. Nat Biotechnol. 2008. PMID: 18297058 Free PMC article.
Rationale and design of the Early valve replacement in severe ASYmptomatic Aortic Stenosis Trial.
Richardson C, Gilbert T, Aslam S, Brookes CL, Singh A, Newby DE, Dweck MR, Stewart R, Myles PS, Briffa T, Selvanayagam J, Chow CK, Murphy GJ, Akowuah EF, Lord J, Barber S, Paola ASD, McCann GP, MBedBiol GSH. Richardson C, et al. Among authors: gilbert t. Am Heart J. 2024 May 29:S0002-8703(24)00128-5. doi: 10.1016/j.ahj.2024.05.013. Online ahead of print. Am Heart J. 2024. PMID: 38821453 Free article.
Associations Between Traumatic Brain Injury and Severity of Tinnitus-Related Functional Impairment Among US Military Veterans: A National, Population-Based Study.
Coco L, Hooker ER, Gilbert TA, Prewitt AL, Reavis KM, O'Neil ME, Clark KD, Henry JA, Zaugg T, Carlson KF. Coco L, et al. Among authors: gilbert ta. J Head Trauma Rehabil. 2024 May-Jun 01;39(3):218-230. doi: 10.1097/HTR.0000000000000896. Epub 2023 Sep 12. J Head Trauma Rehabil. 2024. PMID: 38709830
751 results