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Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers.
J Med Chem. 2018 Nov 21;61(22):10155-10172. doi: 10.1021/acs.jmedchem.8b01318. Epub 2018 Oct 31.
J Med Chem. 2018.
PMID: 30339381
Discovery and Characterization of Allosteric WNK Kinase Inhibitors.
Yamada K, Zhang JH, Xie X, Reinhardt J, Xie AQ, LaSala D, Kohls D, Yowe D, Burdick D, Yoshisue H, Wakai H, Schmidt I, Gunawan J, Yasoshima K, Yue QK, Kato M, Mogi M, Idamakanti N, Kreder N, Drueckes P, Pandey P, Kawanami T, Huang W, Yagi YI, Deng Z, Park HM.
Yamada K, et al. Among authors: yue qk.
ACS Chem Biol. 2016 Dec 16;11(12):3338-3346. doi: 10.1021/acschembio.6b00511. Epub 2016 Oct 19.
ACS Chem Biol. 2016.
PMID: 27712055
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Integrated TK-TD modeling for drug-induced concurrent tachycardia and QT changes in beagle dogs.
Wu F, Heimbach T, Hatsis P, Tang HM, Dugyala R, Yue Q, Wang T, He H.
Wu F, et al.
J Pharmacokinet Pharmacodyn. 2017 Oct;44(5):449-462. doi: 10.1007/s10928-017-9532-2. Epub 2017 Jun 22.
J Pharmacokinet Pharmacodyn. 2017.
PMID: 28643108
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In Vitro and In Vivo Properties of CUO246, a Novel Bacterial DNA Gyrase/Topoisomerase IV Inhibitor.
Blais J, Dean CR, Lapointe G, Leeds JA, Ma S, Morris L, Moser HE, Osborne CS, Prosen KR, Richie D, Skepper C, Thompson K, Vo J, Yue Q, Rivkin A.
Blais J, et al.
Antimicrob Agents Chemother. 2022 Dec 20;66(12):e0092122. doi: 10.1128/aac.00921-22. Epub 2022 Nov 30.
Antimicrob Agents Chemother. 2022.
PMID: 36448795
Free PMC article.
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2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV) (Part 1 - small molecules, peptides and small molecule biomarkers by LCMS).
Yang E, Welink J, Cape S, Woolf E, Sydor J, James C, Goykhman D, Arnold M, Addock N, Bauer R, Buonarati M, Ciccimaro E, Dodda R, Evans C, Garofolo F, Hughes N, Islam R, Nehls C, Wilson A, Briscoe C, Bustard M, Coppola L, Croft S, Drexler D, Ferrari L, Fraier D, Jenkins R, Kadavil J, King L, Li W, Lima Santos GM, Musuku A, Ramanathan R, Saito Y, Savoie N, Summerfield S, Sun R, Tampal N, Vinter S, Wakelin-Smith J, Yue Q.
Yang E, et al.
Bioanalysis. 2016 Nov;8(22):2363-2378. doi: 10.4155/bio-2016-4992. Epub 2016 Oct 7.
Bioanalysis. 2016.
PMID: 27712081
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Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants.
Yue QK, Kass IJ, Sampson NS, Vrielink A.
Yue QK, et al.
Biochemistry. 1999 Apr 6;38(14):4277-86. doi: 10.1021/bi982497j.
Biochemistry. 1999.
PMID: 10194345
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