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Aberrant ORM (yeast)-like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in mice.
Oyeniran C, Sturgill JL, Hait NC, Huang WC, Avni D, Maceyka M, Newton J, Allegood JC, Montpetit A, Conrad DH, Milstien S, Spiegel S. Oyeniran C, et al. Among authors: spiegel s. J Allergy Clin Immunol. 2015 Oct;136(4):1035-46.e6. doi: 10.1016/j.jaci.2015.02.031. Epub 2015 Apr 2. J Allergy Clin Immunol. 2015. PMID: 25842287 Free PMC article.
ORMDL proteins regulate ceramide levels during sterile inflammation.
Cai L, Oyeniran C, Biswas DD, Allegood J, Milstien S, Kordula T, Maceyka M, Spiegel S. Cai L, et al. Among authors: spiegel s. J Lipid Res. 2016 Aug;57(8):1412-22. doi: 10.1194/jlr.M065920. Epub 2016 Jun 16. J Lipid Res. 2016. PMID: 27313060 Free PMC article.
ORMDL3 and allergic asthma: From physiology to pathology.
James B, Milstien S, Spiegel S. James B, et al. Among authors: spiegel s. J Allergy Clin Immunol. 2019 Sep;144(3):634-640. doi: 10.1016/j.jaci.2019.07.023. Epub 2019 Jul 31. J Allergy Clin Immunol. 2019. PMID: 31376405 Free PMC article. Review.
Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells.
Yacoub A, Park MA, Gupta P, Rahmani M, Zhang G, Hamed H, Hanna D, Sarkar D, Lebedeva IV, Emdad L, Sauane M, Vozhilla N, Spiegel S, Koumenis C, Graf M, Curiel DT, Grant S, Fisher PB, Dent P. Yacoub A, et al. Among authors: spiegel s. Mol Cancer Ther. 2008 Feb;7(2):297-313. doi: 10.1158/1535-7163.MCT-07-2166. Mol Cancer Ther. 2008. PMID: 18281515 Free PMC article.
491 results