Nieman M - Search Results

1

The protease-activated receptor 4 Ala120Thr variant alters platelet responsiveness to low-dose thrombin and protease-activated receptor 4 desensitization, and is blocked by non-competitive P2Y₁₂ inhibition.

Whitley MJ, Henke DM, Ghazi A, Nieman M, Stoller M, Simon LM, Chen E, Vesci J, Holinstat M, McKenzie SE, Shaw CA, Edelstein LC, Bray PF. Whitley MJ, et al. Among authors: nieman m. J Thromb Haemost. 2018 Dec;16(12):2501-2514. doi: 10.1111/jth.14318. Epub 2018 Nov 22. J Thromb Haemost. 2018. PMID: 30347494 Free PMC article.

2

Thrombostatin FM compounds: direct thrombin inhibitors - mechanism of action in vitro and in vivo.

Nieman MT, Burke F, Warnock M, Zhou Y, Sweigart J, Chen A, Ricketts D, Lucchesi BR, Chen Z, Di Cera E, Hilfinger J, Kim JS, Mosberg HI, Schmaier AH. Nieman MT, et al. J Thromb Haemost. 2008 May;6(5):837-45. doi: 10.1111/j.1538-7836.2008.02937.x. Epub 2008 Feb 25. J Thromb Haemost. 2008. PMID: 18315550 Free PMC article.

3

Oral thrombostatin FM19 inhibits prostate cancer.

Nieman MT, LaRusch G, Fang C, Zhou Y, Schmaier AH. Nieman MT, et al. Thromb Haemost. 2010 Nov;104(5):1044-8. doi: 10.1160/TH09-08-0570. Epub 2010 Sep 30. Thromb Haemost. 2010. PMID: 20886199 Free PMC article.

4

Calcium mobilization and protein kinase C activation downstream of protease activated receptor 4 (PAR4) is negatively regulated by PAR3 in mouse platelets.

Arachiche A, de la Fuente M, Nieman MT. Arachiche A, et al. Among authors: nieman mt. PLoS One. 2013;8(2):e55740. doi: 10.1371/journal.pone.0055740. Epub 2013 Feb 6. PLoS One. 2013. PMID: 23405206 Free PMC article.

5

Protease-activated receptor 1 (PAR1) and PAR4 heterodimers are required for PAR1-enhanced cleavage of PAR4 by α-thrombin.

Arachiche A, Mumaw MM, de la Fuente M, Nieman MT. Arachiche A, et al. Among authors: nieman mt. J Biol Chem. 2013 Nov 8;288(45):32553-32562. doi: 10.1074/jbc.M113.472373. Epub 2013 Oct 4. J Biol Chem. 2013. PMID: 24097976 Free PMC article.

6

Targeting the anionic region of human protease-activated receptor 4 inhibits platelet aggregation and thrombosis without interfering with hemostasis.

Mumaw MM, de la Fuente M, Noble DN, Nieman MT. Mumaw MM, et al. Among authors: nieman mt. J Thromb Haemost. 2014 Aug;12(8):1331-41. doi: 10.1111/jth.12619. Epub 2014 Jun 27. J Thromb Haemost. 2014. PMID: 24888424 Free PMC article.

7

Common variants in the human platelet PAR4 thrombin receptor alter platelet function and differ by race.

Edelstein LC, Simon LM, Lindsay CR, Kong X, Teruel-Montoya R, Tourdot BE, Chen ES, Ma L, Coughlin S, Nieman M, Holinstat M, Shaw CA, Bray PF. Edelstein LC, et al. Among authors: nieman m. Blood. 2014 Nov 27;124(23):3450-8. doi: 10.1182/blood-2014-04-572479. Epub 2014 Oct 7. Blood. 2014. PMID: 25293779 Free PMC article.

8

Development and characterization of monoclonal antibodies against Protease Activated Receptor 4 (PAR4).

Mumaw MM, de la Fuente M, Arachiche A, Wahl JK 3rd, Nieman MT. Mumaw MM, et al. Among authors: nieman mt. Thromb Res. 2015 Jun;135(6):1165-71. doi: 10.1016/j.thromres.2015.03.027. Epub 2015 Apr 9. Thromb Res. 2015. PMID: 25890453 Free PMC article.

9

Protease-activated receptors in hemostasis.

Nieman MT. Nieman MT. Blood. 2016 Jul 14;128(2):169-77. doi: 10.1182/blood-2015-11-636472. Epub 2016 Apr 28. Blood. 2016. PMID: 27127302 Free PMC article. Review.

10

Platelet microparticles infiltrating solid tumors transfer miRNAs that suppress tumor growth.

Michael JV, Wurtzel JGT, Mao GF, Rao AK, Kolpakov MA, Sabri A, Hoffman NE, Rajan S, Tomar D, Madesh M, Nieman MT, Yu J, Edelstein LC, Rowley JW, Weyrich AS, Goldfinger LE. Michael JV, et al. Among authors: nieman mt. Blood. 2017 Aug 3;130(5):567-580. doi: 10.1182/blood-2016-11-751099. Epub 2017 May 12. Blood. 2017. PMID: 28500171 Free PMC article.

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