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Functional redundancy between RAP1 isoforms in murine platelet production and function.
Stefanini L, Lee RH, Paul DS, O'Shaughnessy EC, Ghalloussi D, Jones CI, Boulaftali Y, Poe KO, Piatt R, Kechele DO, Caron KM, Hahn KM, Gibbins JM, Bergmeier W. Stefanini L, et al. Blood. 2018 Nov 1;132(18):1951-1962. doi: 10.1182/blood-2018-03-838714. Epub 2018 Aug 21. Blood. 2018. PMID: 30131434 Free PMC article.
Rap1-Rac1 circuits potentiate platelet activation.
Stefanini L, Boulaftali Y, Ouellette TD, Holinstat M, Désiré L, Leblond B, Andre P, Conley PB, Bergmeier W. Stefanini L, et al. Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):434-41. doi: 10.1161/ATVBAHA.111.239194. Epub 2011 Nov 10. Arterioscler Thromb Vasc Biol. 2012. PMID: 22075250 Free PMC article.
RASA3 is a critical inhibitor of RAP1-dependent platelet activation.
Stefanini L, Paul DS, Robledo RF, Chan ER, Getz TM, Campbell RA, Kechele DO, Casari C, Piatt R, Caron KM, Mackman N, Weyrich AS, Parrott MC, Boulaftali Y, Adams MD, Peters LL, Bergmeier W. Stefanini L, et al. J Clin Invest. 2015 Apr;125(4):1419-32. doi: 10.1172/JCI77993. Epub 2015 Feb 23. J Clin Invest. 2015. PMID: 25705885 Free PMC article.
RAP GTPases and platelet integrin signaling.
Stefanini L, Bergmeier W. Stefanini L, et al. Platelets. 2019;30(1):41-47. doi: 10.1080/09537104.2018.1476681. Epub 2018 Jun 4. Platelets. 2019. PMID: 29863951 Free PMC article. Review.
RAP1-GTPase signaling and platelet function.
Stefanini L, Bergmeier W. Stefanini L, et al. J Mol Med (Berl). 2016 Jan;94(1):13-9. doi: 10.1007/s00109-015-1346-3. Epub 2015 Oct 1. J Mol Med (Berl). 2016. PMID: 26423530 Free PMC article. Review.
Subcellular localization of Rap1 GTPase activator CalDAG-GEFI is orchestrated by interaction of its atypical C1 domain with membrane phosphoinositides.
Sarker M, Goliaei A, Golesi F, Poggi M, Cook AA, Khan MAI, Temple BR, Stefanini L, Canault M, Bergmeier W, Campbell SL. Sarker M, et al. Among authors: stefanini l. J Thromb Haemost. 2020 Mar;18(3):693-705. doi: 10.1111/jth.14687. Epub 2019 Dec 30. J Thromb Haemost. 2020. PMID: 31758832 Free PMC article.
Platelet signaling--blood's great balancing act.
Bergmeier W, Stefanini L. Bergmeier W, et al. Among authors: stefanini l. Oncotarget. 2015 Aug 21;6(24):19922-3. doi: 10.18632/oncotarget.5122. Oncotarget. 2015. PMID: 26343368 Free PMC article. No abstract available.
Negative regulators of platelet activation and adhesion.
Stefanini L, Bergmeier W. Stefanini L, et al. J Thromb Haemost. 2018 Feb;16(2):220-230. doi: 10.1111/jth.13910. Epub 2017 Dec 26. J Thromb Haemost. 2018. PMID: 29193689 Free PMC article. Review.
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