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YbtT is a low-specificity type II thioesterase that maintains production of the metallophore yersiniabactin in pathogenic enterobacteria.
J Biol Chem. 2018 Dec 21;293(51):19572-19585. doi: 10.1074/jbc.RA118.005752. Epub 2018 Oct 24.
J Biol Chem. 2018.
PMID: 30355735
Free PMC article.
Enterobacteria secrete an inhibitor of Pseudomonas virulence during clinical bacteriuria.
Ohlemacher SI, Giblin DE, d'Avignon DA, Stapleton AE, Trautner BW, Henderson JP.
Ohlemacher SI, et al.
J Clin Invest. 2017 Nov 1;127(11):4018-4030. doi: 10.1172/JCI92464. Epub 2017 Sep 25.
J Clin Invest. 2017.
PMID: 28945201
Free PMC article.
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Lentzeacins A-E, New Bacterial-Derived 2,5- and 2,6-Disubstituted Pyrazines from a BGC-Rich Soil Bacterium Lentzea sp. GA3-008.
Liu HB, Davison JR, Rajwani R, Zhao G, Ohlemacher SI, O'Connor RD, Bewley CA.
Liu HB, et al. Among authors: ohlemacher si.
Molecules. 2021 Nov 27;26(23):7197. doi: 10.3390/molecules26237197.
Molecules. 2021.
PMID: 34885778
Free PMC article.
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Genome-Guided Discovery of Natural Products through Multiplexed Low-Coverage Whole-Genome Sequencing of Soil Actinomycetes on Oxford Nanopore Flongle.
Rajwani R, Ohlemacher SI, Zhao G, Liu HB, Bewley CA.
Rajwani R, et al. Among authors: ohlemacher si.
mSystems. 2021 Dec 21;6(6):e0102021. doi: 10.1128/mSystems.01020-21. Epub 2021 Nov 23.
mSystems. 2021.
PMID: 34812649
Free PMC article.
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Structural Basis for a Dual Function ATP Grasp Ligase That Installs Single and Bicyclic ω-Ester Macrocycles in a New Multicore RiPP Natural Product.
Zhao G, Kosek D, Liu HB, Ohlemacher SI, Blackburne B, Nikolskaya A, Makarova KS, Sun J, Barry Iii CE, Koonin EV, Dyda F, Bewley CA.
Zhao G, et al. Among authors: ohlemacher si.
J Am Chem Soc. 2021 Jun 2;143(21):8056-8068. doi: 10.1021/jacs.1c02316. Epub 2021 May 24.
J Am Chem Soc. 2021.
PMID: 34028251
Free PMC article.
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Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding.
Doyle MT, Jimah JR, Dowdy T, Ohlemacher SI, Larion M, Hinshaw JE, Bernstein HD.
Doyle MT, et al. Among authors: ohlemacher si.
Cell. 2022 Mar 31;185(7):1143-1156.e13. doi: 10.1016/j.cell.2022.02.016. Epub 2022 Mar 15.
Cell. 2022.
PMID: 35294859
Free PMC article.
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TGF-β uncouples glycolysis and inflammation in macrophages and controls survival during sepsis.
Gauthier T, Yao C, Dowdy T, Jin W, Lim YJ, Patiño LC, Liu N, Ohlemacher SI, Bynum A, Kazmi R, Bewley CA, Mitrovic M, Martin D, Morell RJ, Eckhaus M, Larion M, Tussiwand R, O'Shea JJ, Chen W.
Gauthier T, et al. Among authors: ohlemacher si.
Sci Signal. 2023 Aug 8;16(797):eade0385. doi: 10.1126/scisignal.ade0385. Epub 2023 Aug 8.
Sci Signal. 2023.
PMID: 37552767
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