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The chromatin accessibility landscape of primary human cancers.
Corces MR, Granja JM, Shams S, Louie BH, Seoane JA, Zhou W, Silva TC, Groeneveld C, Wong CK, Cho SW, Satpathy AT, Mumbach MR, Hoadley KA, Robertson AG, Sheffield NC, Felau I, Castro MAA, Berman BP, Staudt LM, Zenklusen JC, Laird PW, Curtis C; Cancer Genome Atlas Analysis Network; Greenleaf WJ, Chang HY. Corces MR, et al. Among authors: sheffield nc. Science. 2018 Oct 26;362(6413):eaav1898. doi: 10.1126/science.aav1898. Science. 2018. PMID: 30361341 Free PMC article.
Single-cell epigenomic variability reveals functional cancer heterogeneity.
Litzenburger UM, Buenrostro JD, Wu B, Shen Y, Sheffield NC, Kathiria A, Greenleaf WJ, Chang HY. Litzenburger UM, et al. Among authors: sheffield nc. Genome Biol. 2017 Jan 24;18(1):15. doi: 10.1186/s13059-016-1133-7. Genome Biol. 2017. PMID: 28118844 Free PMC article.
Refgenie: a reference genome resource manager.
Stolarczyk M, Reuter VP, Smith JP, Magee NE, Sheffield NC. Stolarczyk M, et al. Among authors: sheffield nc. Gigascience. 2020 Feb 1;9(2):giz149. doi: 10.1093/gigascience/giz149. Gigascience. 2020. PMID: 31995185 Free PMC article.
Analytical Approaches for ATAC-seq Data Analysis.
Smith JP, Sheffield NC. Smith JP, et al. Among authors: sheffield nc. Curr Protoc Hum Genet. 2020 Jun;106(1):e101. doi: 10.1002/cphg.101. Curr Protoc Hum Genet. 2020. PMID: 32543102 Free PMC article.
COCOA: coordinate covariation analysis of epigenetic heterogeneity.
Lawson JT, Smith JP, Bekiranov S, Garrett-Bakelman FE, Sheffield NC. Lawson JT, et al. Among authors: sheffield nc. Genome Biol. 2020 Sep 7;21(1):240. doi: 10.1186/s13059-020-02139-4. Genome Biol. 2020. PMID: 32894181 Free PMC article.
The accessible chromatin landscape of the human genome.
Thurman RE, Rynes E, Humbert R, Vierstra J, Maurano MT, Haugen E, Sheffield NC, Stergachis AB, Wang H, Vernot B, Garg K, John S, Sandstrom R, Bates D, Boatman L, Canfield TK, Diegel M, Dunn D, Ebersol AK, Frum T, Giste E, Johnson AK, Johnson EM, Kutyavin T, Lajoie B, Lee BK, Lee K, London D, Lotakis D, Neph S, Neri F, Nguyen ED, Qu H, Reynolds AP, Roach V, Safi A, Sanchez ME, Sanyal A, Shafer A, Simon JM, Song L, Vong S, Weaver M, Yan Y, Zhang Z, Zhang Z, Lenhard B, Tewari M, Dorschner MO, Hansen RS, Navas PA, Stamatoyannopoulos G, Iyer VR, Lieb JD, Sunyaev SR, Akey JM, Sabo PJ, Kaul R, Furey TS, Dekker J, Crawford GE, Stamatoyannopoulos JA. Thurman RE, et al. Among authors: sheffield nc. Nature. 2012 Sep 6;489(7414):75-82. doi: 10.1038/nature11232. Nature. 2012. PMID: 22955617 Free PMC article.
58 results