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CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism.
Dorr CR, Remmel RP, Muthusamy A, Fisher J, Moriarity BS, Yasuda K, Wu B, Guan W, Schuetz EG, Oetting WS, Jacobson PA, Israni AK. Dorr CR, et al. Among authors: muthusamy a. Drug Metab Dispos. 2017 Aug;45(8):957-965. doi: 10.1124/dmd.117.076307. Epub 2017 May 22. Drug Metab Dispos. 2017. PMID: 28533324 Free PMC article.
Identification of genetic variants associated with tacrolimus metabolism in kidney transplant recipients by extreme phenotype sampling and next generation sequencing.
Dorr CR, Wu B, Remmel RP, Muthusamy A, Schladt DP, Abrahante JE, Guan W, Mannon RB, Matas AJ, Oetting WS, Jacobson PA, Israni AK; for DeKAF Genomics. Dorr CR, et al. Among authors: muthusamy a. Pharmacogenomics J. 2019 Aug;19(4):375-389. doi: 10.1038/s41397-018-0063-z. Epub 2018 Nov 16. Pharmacogenomics J. 2019. PMID: 30442921 Free PMC article.
Extreme Phenotype Sampling and Next Generation Sequencing to Identify Genetic Variants Associated with Tacrolimus in African American Kidney Transplant Recipients.
Mohamed M, Guo B, Wu B, Schladt D, Muthusamy A, Guan W, Abrahante J, Onyeaghala G, Saqr A, Pankratz N, Agarwal G, Mannon R, Matas A, Oetting W, Remmel R, Israni A, Jacobson P, Dorr C. Mohamed M, et al. Among authors: muthusamy a. Res Sq [Preprint]. 2024 Mar 14:rs.3.rs-4050136. doi: 10.21203/rs.3.rs-4050136/v1. Res Sq. 2024. PMID: 38558983 Free PMC article. Preprint.
EUS-guided therapies for primary and secondary prophylaxis in gastric varices-An updated systematic review and meta-analysis.
Chandan S, Nguyen AK, Mohan BP, Deliwala S, Ramai D, Kassab LL, Muthusamy A, Facciorusso A, Kamal F, Bilal M, Samanta J, Adler DG. Chandan S, et al. Among authors: muthusamy a. Endosc Ultrasound. 2023 Jul-Aug;12(4):351-361. doi: 10.1097/eus.0000000000000017. Epub 2023 Sep 13. Endosc Ultrasound. 2023. PMID: 37795350 Free PMC article.
122 results