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Identification of quercitrin as an inhibitor of the p90 S6 ribosomal kinase (RSK): structure of its complex with the N-terminal domain of RSK2 at 1.8 Å resolution.
Derewenda U, Artamonov M, Szukalska G, Utepbergenov D, Olekhnovich N, Parikh HI, Kellogg GE, Somlyo AV, Derewenda ZS. Derewenda U, et al. Among authors: derewenda zs. Acta Crystallogr D Biol Crystallogr. 2013 Feb;69(Pt 2):266-75. doi: 10.1107/S0907444912045520. Epub 2013 Jan 19. Acta Crystallogr D Biol Crystallogr. 2013. PMID: 23385462 Free PMC article.
Agonist-induced Ca2+ sensitization in smooth muscle: redundancy of Rho guanine nucleotide exchange factors (RhoGEFs) and response kinetics, a caged compound study.
Artamonov MV, Momotani K, Stevenson A, Trentham DR, Derewenda U, Derewenda ZS, Read PW, Gutkind JS, Somlyo AV. Artamonov MV, et al. Among authors: derewenda u, derewenda zs. J Biol Chem. 2013 Nov 22;288(47):34030-34040. doi: 10.1074/jbc.M113.514596. Epub 2013 Oct 8. J Biol Chem. 2013. PMID: 24106280 Free PMC article.
Insights into the inhibition of the p90 ribosomal S6 kinase (RSK) by the flavonol glycoside SL0101 from the 1.5 Å crystal structure of the N-terminal domain of RSK2 with bound inhibitor.
Utepbergenov D, Derewenda U, Olekhnovich N, Szukalska G, Banerjee B, Hilinski MK, Lannigan DA, Stukenberg PT, Derewenda ZS. Utepbergenov D, et al. Among authors: derewenda u, derewenda zs. Biochemistry. 2012 Aug 21;51(33):6499-510. doi: 10.1021/bi300620c. Epub 2012 Aug 6. Biochemistry. 2012. PMID: 22846040 Free PMC article.
141 results