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Toward a Ferrous Iron-Cleavable Linker for Antibody-Drug Conjugates.
Spangler B, Kline T, Hanson J, Li X, Zhou S, Wells JA, Sato AK, Renslo AR. Spangler B, et al. Among authors: kline t. Mol Pharm. 2018 May 7;15(5):2054-2059. doi: 10.1021/acs.molpharmaceut.8b00242. Epub 2018 Mar 23. Mol Pharm. 2018. PMID: 29569925
Targeting CD74 in multiple myeloma with the novel, site-specific antibody-drug conjugate STRO-001.
Abrahams CL, Li X, Embry M, Yu A, Krimm S, Krueger S, Greenland NY, Wen KW, Jones C, DeAlmeida V, Solis WA, Matheny S, Kline T, Yam AY, Stafford R, Wiita AP, Hallam T, Lupher M, Molina A. Abrahams CL, et al. Among authors: kline t. Oncotarget. 2018 Dec 28;9(102):37700-37714. doi: 10.18632/oncotarget.26491. eCollection 2018 Dec 28. Oncotarget. 2018. PMID: 30701025 Free PMC article.
Methods to Make Homogenous Antibody Drug Conjugates.
Kline T, Steiner AR, Penta K, Sato AK, Hallam TJ, Yin G. Kline T, et al. Pharm Res. 2015 Nov;32(11):3480-93. doi: 10.1007/s11095-014-1596-8. Epub 2014 Dec 16. Pharm Res. 2015. PMID: 25511917 Free PMC article. Review.
Design, synthesis, and evaluation of substituted alkylindoles that activate G protein-coupled receptors distinct from the cannabinoid CB1 and CB2 receptors.
Kline T, Xu C, Kreitzer FR, Hurst DP, Eldeeb KM, Wager-Miller J, Olivas K, Hepburn SA, Huffman JW, Mackie K, Howlett AC, Reggio P, Stella N. Kline T, et al. Eur J Med Chem. 2023 Mar 5;249:115123. doi: 10.1016/j.ejmech.2023.115123. Epub 2023 Jan 26. Eur J Med Chem. 2023. PMID: 36708677 Free PMC article.
359 results