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Cryo-EM structure of the NLRC4CARD filament provides insights into how symmetric and asymmetric supramolecular structures drive inflammasome assembly.
J Biol Chem. 2018 Dec 28;293(52):20240-20248. doi: 10.1074/jbc.RA118.006050. Epub 2018 Nov 1.
J Biol Chem. 2018.
PMID: 30385506
Free PMC article.
Assembly-driven activation of the AIM2 foreign-dsDNA sensor provides a polymerization template for downstream ASC.
Morrone SR, Matyszewski M, Yu X, Delannoy M, Egelman EH, Sohn J.
Morrone SR, et al. Among authors: matyszewski m.
Nat Commun. 2015 Jul 22;6:7827. doi: 10.1038/ncomms8827.
Nat Commun. 2015.
PMID: 26197926
Free PMC article.
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Distinct axial and lateral interactions within homologous filaments dictate the signaling specificity and order of the AIM2-ASC inflammasome.
Matyszewski M, Zheng W, Lueck J, Mazanek Z, Mohideen N, Lau AY, Egelman EH, Sohn J.
Matyszewski M, et al.
Nat Commun. 2021 May 12;12(1):2735. doi: 10.1038/s41467-021-23045-8.
Nat Commun. 2021.
PMID: 33980849
Free PMC article.
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Digital signaling network drives the assembly of the AIM2-ASC inflammasome.
Matyszewski M, Morrone SR, Sohn J.
Matyszewski M, et al.
Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):E1963-E1972. doi: 10.1073/pnas.1712860115. Epub 2018 Feb 12.
Proc Natl Acad Sci U S A. 2018.
PMID: 29440442
Free PMC article.
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IFI16 filament formation in salivary epithelial cells shapes the anti-IFI16 immune response in Sjögren's syndrome.
Antiochos B, Matyszewski M, Sohn J, Casciola-Rosen L, Rosen A.
Antiochos B, et al. Among authors: matyszewski m.
JCI Insight. 2018 Sep 20;3(18):e120179. doi: 10.1172/jci.insight.120179. eCollection 2018 Sep 20.
JCI Insight. 2018.
PMID: 30232276
Free PMC article.
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Preparation of filamentous proteins for electron microscopy visualization and reconstruction.
Matyszewski M, Sohn J.
Matyszewski M, et al.
Methods Enzymol. 2019;625:167-176. doi: 10.1016/bs.mie.2019.06.007. Epub 2019 Jul 2.
Methods Enzymol. 2019.
PMID: 31455526
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Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Deniston CK, Salogiannis J, Mathea S, Snead DM, Lahiri I, Matyszewski M, Donosa O, Watanabe R, Böhning J, Shiau AK, Knapp S, Villa E, Reck-Peterson SL, Leschziner AE.
Deniston CK, et al. Among authors: matyszewski m.
Nature. 2020 Dec;588(7837):344-349. doi: 10.1038/s41586-020-2673-2. Epub 2020 Aug 19.
Nature. 2020.
PMID: 32814344
Free PMC article.
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Structural basis for Parkinson's disease-linked LRRK2's binding to microtubules.
Snead DM, Matyszewski M, Dickey AM, Lin YX, Leschziner AE, Reck-Peterson SL.
Snead DM, et al. Among authors: matyszewski m.
Nat Struct Mol Biol. 2022 Dec;29(12):1196-1207. doi: 10.1038/s41594-022-00863-y. Epub 2022 Dec 12.
Nat Struct Mol Biol. 2022.
PMID: 36510024
Free PMC article.
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