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Arrhythmia initiation in catecholaminergic polymorphic ventricular tachycardia type 1 depends on both heart rate and sympathetic stimulation.
Danielsen TK, Manotheepan R, Sadredini M, Leren IS, Edwards AG, Vincent KP, Lehnart SE, Sejersted OM, Sjaastad I, Haugaa KH, Stokke MK. Danielsen TK, et al. Among authors: lehnart se. PLoS One. 2018 Nov 6;13(11):e0207100. doi: 10.1371/journal.pone.0207100. eCollection 2018. PLoS One. 2018. PMID: 30399185 Free PMC article.
On the Adjacency Matrix of RyR2 Cluster Structures.
Walker MA, Kohl T, Lehnart SE, Greenstein JL, Lederer WJ, Winslow RL. Walker MA, et al. Among authors: lehnart se. PLoS Comput Biol. 2015 Nov 6;11(11):e1004521. doi: 10.1371/journal.pcbi.1004521. eCollection 2015 Nov. PLoS Comput Biol. 2015. PMID: 26545234 Free PMC article.
Sarcoplasmic reticulum calcium leak contributes to arrhythmia but not to heart failure progression.
Mohamed BA, Hartmann N, Tirilomis P, Sekeres K, Li W, Neef S, Richter C, Zeisberg EM, Kattner L, Didié M, Guan K, Schmitto JD, Lehnart SE, Luther S, Voigt N, Seidler T, Sossalla S, Hasenfuss G, Toischer K. Mohamed BA, et al. Among authors: lehnart se. Sci Transl Med. 2018 Sep 12;10(458):eaan0724. doi: 10.1126/scitranslmed.aan0724. Sci Transl Med. 2018. PMID: 30209242
Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia.
Ottesen AH, Carlson CR, Eken OS, Sadredini M, Myhre PL, Shen X, Dalhus B, Laver DR, Lunde PK, Kurola J, Lunde M, Hoff JE, Godang K, Sjaastad I, Pettilä V, Stridsberg M, Lehnart SE, Edwards AG, Lunde IG, Omland T, Stokke MK, Christensen G, Røsjø H, Louch WE. Ottesen AH, et al. Among authors: lehnart se. Circ Arrhythm Electrophysiol. 2019 Apr;12(4):e007045. doi: 10.1161/CIRCEP.118.007045. Circ Arrhythm Electrophysiol. 2019. PMID: 30943765 Free article.
Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial Fibrillation.
Alsina KM, Hulsurkar M, Brandenburg S, Kownatzki-Danger D, Lenz C, Urlaub H, Abu-Taha I, Kamler M, Chiang DY, Lahiri SK, Reynolds JO, Quick AP, Scott L Jr, Word TA, Gelves MD, Heck AJR, Li N, Dobrev D, Lehnart SE, Wehrens XHT. Alsina KM, et al. Among authors: lehnart se. Circulation. 2019 Aug 20;140(8):681-693. doi: 10.1161/CIRCULATIONAHA.119.039642. Epub 2019 Jun 12. Circulation. 2019. PMID: 31185731 Free PMC article.
CaMKII inhibition has dual effects on spontaneous Ca2+ release and Ca2+ alternans in ventricular cardiomyocytes from mice with a gain-of-function RyR2 mutation.
Sadredini M, Haugsten Hansen M, Frisk M, Louch WE, Lehnart SE, Sjaastad I, Stokke MK. Sadredini M, et al. Among authors: lehnart se. Am J Physiol Heart Circ Physiol. 2021 Aug 1;321(2):H446-H460. doi: 10.1152/ajpheart.00011.2021. Epub 2021 Jul 16. Am J Physiol Heart Circ Physiol. 2021. PMID: 34270372 Free article.
Stimulated emission depletion live-cell super-resolution imaging shows proliferative remodeling of T-tubule membrane structures after myocardial infarction.
Wagner E, Lauterbach MA, Kohl T, Westphal V, Williams GS, Steinbrecher JH, Streich JH, Korff B, Tuan HT, Hagen B, Luther S, Hasenfuss G, Parlitz U, Jafri MS, Hell SW, Lederer WJ, Lehnart SE. Wagner E, et al. Among authors: lehnart se. Circ Res. 2012 Aug 3;111(4):402-14. doi: 10.1161/CIRCRESAHA.112.274530. Epub 2012 Jun 21. Circ Res. 2012. PMID: 22723297 Free PMC article.
112 results