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Overcoming EGFRG724S-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors.
Nat Commun. 2018 Nov 7;9(1):4655. doi: 10.1038/s41467-018-07078-0.
Nat Commun. 2018.
PMID: 30405134
Free PMC article.
Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors.
Plenker D, Riedel M, Brägelmann J, Dammert MA, Chauhan R, Knowles PP, Lorenz C, Keul M, Bührmann M, Pagel O, Tischler V, Scheel AH, Schütte D, Song Y, Stark J, Mrugalla F, Alber Y, Richters A, Engel J, Leenders F, Heuckmann JM, Wolf J, Diebold J, Pall G, Peifer M, Aerts M, Gevaert K, Zahedi RP, Buettner R, Shokat KM, McDonald NQ, Kast SM, Gautschi O, Thomas RK, Sos ML.
Plenker D, et al. Among authors: alber y.
Sci Transl Med. 2017 Jun 14;9(394):eaah6144. doi: 10.1126/scitranslmed.aah6144.
Sci Transl Med. 2017.
PMID: 28615362
Free PMC article.
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Structure of a Therapeutic Full-Length Anti-NPRA IgG4 Antibody: Dissecting Conformational Diversity.
Blech M, Hörer S, Kuhn AB, Kube S, Göddeke H, Kiefer H, Zang Y, Alber Y, Kast SM, Westermann M, Tully MD, Schäfer LV, Garidel P.
Blech M, et al. Among authors: alber y.
Biophys J. 2019 May 7;116(9):1637-1649. doi: 10.1016/j.bpj.2019.03.036. Epub 2019 Apr 5.
Biophys J. 2019.
PMID: 31023536
Free PMC article.
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