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Integration of genetics and miRNA-target gene network identified disease biology implicated in tissue specificity.
Sakaue S, Hirata J, Maeda Y, Kawakami E, Nii T, Kishikawa T, Ishigaki K, Terao C, Suzuki K, Akiyama M, Suita N, Masuda T, Ogawa K, Yamamoto K, Saeki Y, Matsushita M, Yoshimura M, Matsuoka H, Ikari K, Taniguchi A, Yamanaka H, Kawaji H, Lassmann T, Itoh M, Yoshitomi H, Ito H, Ohmura K, R Forrest AR, Hayashizaki Y, Carninci P, Kumanogoh A, Kamatani Y, de Hoon M, Yamamoto K, Okada Y. Sakaue S, et al. Among authors: yoshitomi h. Nucleic Acids Res. 2018 Dec 14;46(22):11898-11909. doi: 10.1093/nar/gky1066. Nucleic Acids Res. 2018. PMID: 30407537 Free PMC article.
Myelin basic protein as a novel genetic risk factor in rheumatoid arthritis--a genome-wide study combined with immunological analyses.
Terao C, Ohmura K, Katayama M, Takahashi M, Kokubo M, Diop G, Toda Y, Yamamoto N; Human Disease Genomics Working Group; Rheumatoid Arthritis (RA) Clinical and Genetic Study Consortium; Shinkura R, Shimizu M, Gut I, Heath S, Melchers I, Manabe T, Lathrop M, Mimori T, Yamada R, Matsuda F. Terao C, et al. PLoS One. 2011;6(6):e20457. doi: 10.1371/journal.pone.0020457. Epub 2011 Jun 3. PLoS One. 2011. PMID: 21673997 Free PMC article.
MicroRNA-451 down-regulates neutrophil chemotaxis via p38 MAPK.
Murata K, Yoshitomi H, Furu M, Ishikawa M, Shibuya H, Ito H, Matsuda S. Murata K, et al. Among authors: yoshitomi h. Arthritis Rheumatol. 2014 Mar;66(3):549-59. doi: 10.1002/art.38269. Arthritis Rheumatol. 2014. PMID: 24574214
Dynamics of Type I and Type II Interferon Signature Determines Responsiveness to Anti-TNF Therapy in Rheumatoid Arthritis.
Iwasaki T, Watanabe R, Ito H, Fujii T, Okuma K, Oku T, Hirayama Y, Ohmura K, Murata K, Murakami K, Yoshitomi H, Tanaka M, Matsuda S, Matsuda F, Morinobu A, Hashimoto M. Iwasaki T, et al. Among authors: yoshitomi h. Front Immunol. 2022 Jun 6;13:901437. doi: 10.3389/fimmu.2022.901437. eCollection 2022. Front Immunol. 2022. PMID: 35734167 Free PMC article.
Role of Lysine-Specific Demethylase 1 in Metabolically Integrating Osteoclast Differentiation and Inflammatory Bone Resorption Through Hypoxia-Inducible Factor 1α and E2F1.
Doi K, Murata K, Ito S, Suzuki A, Terao C, Ishie S, Umemoto A, Murotani Y, Nishitani K, Yoshitomi H, Fujii T, Watanabe R, Hashimoto M, Murakami K, Tanaka M, Ito H, Park-Min KH, Ivashkiv LB, Morinobu A, Matsuda S. Doi K, et al. Among authors: yoshitomi h. Arthritis Rheumatol. 2022 Jun;74(6):948-960. doi: 10.1002/art.42074. Epub 2022 Apr 27. Arthritis Rheumatol. 2022. PMID: 35077015 Free PMC article.
Three groups in the 28 joints for rheumatoid arthritis synovitis--analysis using more than 17,000 assessments in the KURAMA database.
Terao C, Hashimoto M, Yamamoto K, Murakami K, Ohmura K, Nakashima R, Yamakawa N, Yoshifuji H, Yukawa N, Kawabata D, Usui T, Yoshitomi H, Furu M, Yamada R, Matsuda F, Ito H, Fujii T, Mimori T. Terao C, et al. Among authors: yoshitomi h. PLoS One. 2013;8(3):e59341. doi: 10.1371/journal.pone.0059341. Epub 2013 Mar 12. PLoS One. 2013. PMID: 23555018 Free PMC article.
490 results