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RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer.
Wang W, Marinis JM, Beal AM, Savadkar S, Wu Y, Khan M, Taunk PS, Wu N, Su W, Wu J, Ahsan A, Kurz E, Chen T, Yaboh I, Li F, Gutierrez J, Diskin B, Hundeyin M, Reilly M, Lich JD, Harris PA, Mahajan MK, Thorpe JH, Nassau P, Mosley JE, Leinwand J, Kochen Rossi JA, Mishra A, Aykut B, Glacken M, Ochi A, Verma N, Kim JI, Vasudevaraja V, Adeegbe D, Almonte C, Bagdatlioglu E, Cohen DJ, Wong KK, Bertin J, Miller G. Wang W, et al. Among authors: ochi a. Cancer Cell. 2018 Nov 12;34(5):757-774.e7. doi: 10.1016/j.ccell.2018.10.006. Cancer Cell. 2018. PMID: 30423296 Free PMC article.
Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance.
Daley D, Mani VR, Mohan N, Akkad N, Ochi A, Heindel DW, Lee KB, Zambirinis CP, Pandian GSB, Savadkar S, Torres-Hernandez A, Nayak S, Wang D, Hundeyin M, Diskin B, Aykut B, Werba G, Barilla RM, Rodriguez R, Chang S, Gardner L, Mahal LK, Ueberheide B, Miller G. Daley D, et al. Among authors: ochi a. Nat Med. 2017 May;23(5):556-567. doi: 10.1038/nm.4314. Epub 2017 Apr 10. Nat Med. 2017. PMID: 28394331 Free PMC article.
RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer.
Wang W, Marinis JM, Beal AM, Savadkar S, Wu Y, Khan M, Taunk PS, Wu N, Su W, Wu J, Ahsan A, Kurz E, Chen T, Yaboh I, Li F, Gutierrez J, Diskin B, Hundeyin M, Reilly M, Lich JD, Harris PA, Mahajan MK, Thorpe JH, Nassau P, Mosley JE, Leinwand J, Kochen Rossi JA, Mishra A, Aykut B, Glacken M, Ochi A, Verma N, Kim JI, Vasudevaraja V, Adeegbe D, Almonte C, Bagdatlioglu E, Cohen DJ, Wong KK, Bertin J, Miller G. Wang W, et al. Among authors: ochi a. Cancer Cell. 2020 Oct 12;38(4):585-590. doi: 10.1016/j.ccell.2020.09.020. Cancer Cell. 2020. PMID: 33049209 Free article. No abstract available.
The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression.
Seifert L, Werba G, Tiwari S, Giao Ly NN, Alothman S, Alqunaibit D, Avanzi A, Barilla R, Daley D, Greco SH, Torres-Hernandez A, Pergamo M, Ochi A, Zambirinis CP, Pansari M, Rendon M, Tippens D, Hundeyin M, Mani VR, Hajdu C, Engle D, Miller G. Seifert L, et al. Among authors: ochi a. Nature. 2016 Apr 14;532(7598):245-9. doi: 10.1038/nature17403. Epub 2016 Apr 6. Nature. 2016. PMID: 27049944 Free PMC article.
Author Correction: Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance.
Daley D, Mani VR, Mohan N, Akkad N, Ochi A, Heindel DW, Lee KB, Zambirinis CP, Pandian GSDB, Savadkar S, Torres-Hernandez A, Nayak S, Wang D, Hundeyin M, Diskin B, Aykut B, Werba G, Barilla RM, Rodriguez R, Chang S, Gardner L, Mahal LK, Ueberheide B, Miller G. Daley D, et al. Among authors: ochi a. Nat Med. 2021 Dec;27(12):2247-2248. doi: 10.1038/s41591-021-01428-0. Nat Med. 2021. PMID: 34845391 No abstract available.
Mincle suppresses Toll-like receptor 4 activation.
Greco SH, Mahmood SK, Vahle AK, Ochi A, Batel J, Deutsch M, Barilla R, Seifert L, Pachter HL, Daley D, Torres-Hernandez A, Hundeyin M, Mani VR, Miller G. Greco SH, et al. Among authors: ochi a. J Leukoc Biol. 2016 Jul;100(1):185-94. doi: 10.1189/jlb.3A0515-185R. Epub 2016 Jan 8. J Leukoc Biol. 2016. PMID: 26747838 Free PMC article.
Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury.
Deutsch M, Graffeo CS, Rokosh R, Pansari M, Ochi A, Levie EM, Van Heerden E, Tippens DM, Greco S, Barilla R, Tomkötter L, Zambirinis CP, Avanzi N, Gulati R, Pachter HL, Torres-Hernandez A, Eisenthal A, Daley D, Miller G. Deutsch M, et al. Among authors: ochi a. Cell Death Dis. 2015 May 7;6(5):e1759. doi: 10.1038/cddis.2015.126. Cell Death Dis. 2015. PMID: 25950489 Free PMC article.
Mincle Signaling Promotes Con A Hepatitis.
Greco SH, Torres-Hernandez A, Kalabin A, Whiteman C, Rokosh R, Ravirala S, Ochi A, Gutierrez J, Salyana MA, Mani VR, Nagaraj SV, Deutsch M, Seifert L, Daley D, Barilla R, Hundeyin M, Nikifrov Y, Tejada K, Gelb BE, Katz SC, Miller G. Greco SH, et al. Among authors: ochi a. J Immunol. 2016 Oct 1;197(7):2816-27. doi: 10.4049/jimmunol.1600598. Epub 2016 Aug 24. J Immunol. 2016. PMID: 27559045 Free PMC article.
Toll-like receptor 7 regulates pancreatic carcinogenesis in mice and humans.
Ochi A, Graffeo CS, Zambirinis CP, Rehman A, Hackman M, Fallon N, Barilla RM, Henning JR, Jamal M, Rao R, Greco S, Deutsch M, Medina-Zea MV, Bin Saeed U, Ego-Osuala MO, Hajdu C, Miller G. Ochi A, et al. J Clin Invest. 2012 Nov;122(11):4118-29. doi: 10.1172/JCI63606. J Clin Invest. 2012. PMID: 23023703 Free PMC article.
Dectin-1 Regulates Hepatic Fibrosis and Hepatocarcinogenesis by Suppressing TLR4 Signaling Pathways.
Seifert L, Deutsch M, Alothman S, Alqunaibit D, Werba G, Pansari M, Pergamo M, Ochi A, Torres-Hernandez A, Levie E, Tippens D, Greco SH, Tiwari S, Ly NNG, Eisenthal A, van Heerden E, Avanzi A, Barilla R, Zambirinis CP, Rendon M, Daley D, Pachter HL, Hajdu C, Miller G. Seifert L, et al. Among authors: ochi a. Cell Rep. 2015 Dec 1;13(9):1909-1921. doi: 10.1016/j.celrep.2015.10.058. Epub 2015 Nov 19. Cell Rep. 2015. PMID: 26655905 Free PMC article.
706 results