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A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice.
Dev Cell. 2018 Nov 19;47(4):509-523.e5. doi: 10.1016/j.devcel.2018.10.027.
Dev Cell. 2018.
PMID: 30458140
Free PMC article.
Developing models of cholangiocarcinoma to close the translational gap in cancer research.
Waddell SH, Boulter L.
Waddell SH, et al.
Expert Opin Investig Drugs. 2021 Apr;30(4):439-450. doi: 10.1080/13543784.2021.1882993. Epub 2021 Feb 14.
Expert Opin Investig Drugs. 2021.
PMID: 33513027
Review.
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In Vivo Modeling of Patient Genetic Heterogeneity Identifies New Ways to Target Cholangiocarcinoma.
Younger NT, Wilson ML, Martinez Lyons A, Jarman EJ, Meynert AM, Grimes GR, Gournopanos K, Waddell SH, Tennant PA, Wilson DH, Guest RV, Wigmore SJ, Acosta JC, Kendall TJ, Taylor MS, Sproul D, Mill P, Boulter L.
Younger NT, et al. Among authors: waddell sh.
Cancer Res. 2022 Apr 15;82(8):1548-1559. doi: 10.1158/0008-5472.CAN-21-2556.
Cancer Res. 2022.
PMID: 35074757
Free PMC article.
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DKK1 drives immune suppressive phenotypes in intrahepatic cholangiocarcinoma and can be targeted with anti-DKK1 therapeutic DKN-01.
Jarman EJ, Horcas-Lopez M, Waddell SH, MacMaster S, Gournopanos K, Soong DYH, Musialik KI, Tsokkou P, Ng ME, Cambridge WA, Wilson DH, Kagey MH, Newman W, Pollard JW, Boulter L.
Jarman EJ, et al. Among authors: waddell sh.
Liver Int. 2023 Jan;43(1):208-220. doi: 10.1111/liv.15383. Epub 2022 Sep 15.
Liver Int. 2023.
PMID: 35924447
Free PMC article.
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A TGFβ-ECM-integrin signaling axis drives structural reconfiguration of the bile duct to promote polycystic liver disease.
Waddell SH, Yao Y, Olaizola P, Walker A, Jarman EJ, Gournopanos K, Gradinaru A, Christodoulou E, Gautier P, Boerrigter MM, Cadamuro M, Fabris L, Drenth JP, Kendall TJ, Banales JM, Khamseh A, Mill P, Boulter L.
Waddell SH, et al.
Sci Transl Med. 2023 Sep 13;15(713):eabq5930. doi: 10.1126/scitranslmed.abq5930. Epub 2023 Sep 13.
Sci Transl Med. 2023.
PMID: 37703354
Free PMC article.
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Van Gogh-like 2 is essential for the architectural patterning of the mammalian biliary tree.
Raab M, Christodoulou E, Krishnankutty R, Gradinaru A, Walker AD, Olaizola P, Younger NT, Lyons AM, Jarman EJ, Gournopanos K, von Kriegsheim A, Waddell SH, Boulter L.
Raab M, et al. Among authors: waddell sh.
J Hepatol. 2024 Mar 7:S0168-8278(24)00149-1. doi: 10.1016/j.jhep.2024.02.030. Online ahead of print.
J Hepatol. 2024.
PMID: 38460794
Free article.
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Non-canonical Wnt signalling regulates scarring in biliary disease via the planar cell polarity receptors.
Wilson DH, Jarman EJ, Mellin RP, Wilson ML, Waddell SH, Tsokkou P, Younger NT, Raven A, Bhalla SR, Noll ATR, Olde Damink SW, Schaap FG, Chen P, Bates DO, Banales JM, Dean CH, Henderson DJ, Sansom OJ, Kendall TJ, Boulter L.
Wilson DH, et al. Among authors: waddell sh.
Nat Commun. 2020 Jan 23;11(1):445. doi: 10.1038/s41467-020-14283-3.
Nat Commun. 2020.
PMID: 31974352
Free PMC article.
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Indian Hedgehog release from TNF-activated renal epithelia drives local and remote organ fibrosis.
O'Sullivan ED, Mylonas KJ, Xin C, Baird DP, Carvalho C, Docherty MH, Campbell R, Matchett KP, Waddell SH, Walker AD, Gallagher KM, Jia S, Leung S, Laird A, Wilflingseder J, Willi M, Reck M, Finnie S, Pisco A, Gordon-Keylock S, Medvinsky A, Boulter L, Henderson NC, Kirschner K, Chandra T, Conway BR, Hughes J, Denby L, Bonventre JV, Ferenbach DA.
O'Sullivan ED, et al. Among authors: waddell sh.
Sci Transl Med. 2023 May 31;15(698):eabn0736. doi: 10.1126/scitranslmed.abn0736. Epub 2023 May 31.
Sci Transl Med. 2023.
PMID: 37256934
Free article.
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