Bartolome A - Search Results

1

Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis.

Zhu C, Kim K, Wang X, Bartolome A, Salomao M, Dongiovanni P, Meroni M, Graham MJ, Yates KP, Diehl AM, Schwabe RF, Tabas I, Valenti L, Lavine JE, Pajvani UB. Zhu C, et al. Among authors: bartolome a. Sci Transl Med. 2018 Nov 21;10(468):eaat0344. doi: 10.1126/scitranslmed.aat0344. Sci Transl Med. 2018. PMID: 30463916 Free PMC article.

2

MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling.

Bartolomé A, García-Aguilar A, Asahara SI, Kido Y, Guillén C, Pajvani UB, Benito M. Bartolomé A, et al. Mol Cell Biol. 2017 Nov 13;37(23):e00441-17. doi: 10.1128/MCB.00441-17. Print 2017 Dec 1. Mol Cell Biol. 2017. PMID: 28894028 Free PMC article.

3

Notch signaling dynamically regulates adult β cell proliferation and maturity.

Bartolome A, Zhu C, Sussel L, Pajvani UB. Bartolome A, et al. J Clin Invest. 2019 Jan 2;129(1):268-280. doi: 10.1172/JCI98098. Epub 2018 Dec 3. J Clin Invest. 2019. PMID: 30375986 Free PMC article.

4

Angiotensin converting enzyme 2 is a novel target of the γ-secretase complex.

Bartolomé A, Liang J, Wang P, Ho DD, Pajvani UB. Bartolomé A, et al. bioRxiv [Preprint]. 2020 Sep 1:2020.09.01.277954. doi: 10.1101/2020.09.01.277954. bioRxiv. 2020. PMID: 32908985 Free PMC article. Updated. Preprint.

5

Notch activity characterizes a common hepatocellular carcinoma subtype with unique molecular and clinicopathologic features.

Zhu C, Ho YJ, Salomao MA, Dapito DH, Bartolome A, Schwabe RF, Lee JS, Lowe SW, Pajvani UB. Zhu C, et al. Among authors: bartolome a. J Hepatol. 2021 Mar;74(3):613-626. doi: 10.1016/j.jhep.2020.09.032. Epub 2020 Oct 8. J Hepatol. 2021. PMID: 33038431 Free PMC article.

6

MTOR and Beta Cell Adaptation in T2D.

Bartolomé A, Pajvani UB. Bartolomé A, et al. J Clin Endocrinol Metab. 2021 Mar 8;106(3):e1466-e1467. doi: 10.1210/clinem/dgaa906. J Clin Endocrinol Metab. 2021. PMID: 33274365 Free PMC article. No abstract available.

7

Angiotensin converting enzyme 2 is a novel target of the γ-secretase complex.

Bartolomé A, Liang J, Wang P, Ho DD, Pajvani UB. Bartolomé A, et al. Sci Rep. 2021 May 7;11(1):9803. doi: 10.1038/s41598-021-89379-x. Sci Rep. 2021. PMID: 33963249 Free PMC article.

8

Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis.

Yu J, Zhu C, Wang X, Kim K, Bartolome A, Dongiovanni P, Yates KP, Valenti L, Carrer M, Sadowski T, Qiang L, Tabas I, Lavine JE, Pajvani UB. Yu J, et al. Among authors: bartolome a. Sci Transl Med. 2021 Jun 23;13(599):eabe1692. doi: 10.1126/scitranslmed.abe1692. Sci Transl Med. 2021. PMID: 34162749 Free PMC article.

9

Notch-mediated Ephrin signaling disrupts islet architecture and β cell function.

Bartolomé A, Suda N, Yu J, Zhu C, Son J, Ding H, Califano A, Accili D, Pajvani UB. Bartolomé A, et al. JCI Insight. 2022 Mar 22;7(6):e157694. doi: 10.1172/jci.insight.157694. JCI Insight. 2022. PMID: 35167496 Free PMC article.

10

MafA Regulation in β-Cells: From Transcriptional to Post-Translational Mechanisms.

Liang J, Chirikjian M, Pajvani UB, Bartolomé A. Liang J, et al. Among authors: bartolome a. Biomolecules. 2022 Mar 31;12(4):535. doi: 10.3390/biom12040535. Biomolecules. 2022. PMID: 35454124 Free PMC article. Review.

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