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Targets and genomic constraints of ectopic Dnmt3b expression.
Zhang Y, Charlton J, Karnik R, Beerman I, Smith ZD, Gu H, Boyle P, Mi X, Clement K, Pop R, Gnirke A, Rossi DJ, Meissner A. Zhang Y, et al. Among authors: karnik r. Elife. 2018 Nov 23;7:e40757. doi: 10.7554/eLife.40757. Elife. 2018. PMID: 30468428 Free PMC article.
Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells.
Liao J, Karnik R, Gu H, Ziller MJ, Clement K, Tsankov AM, Akopian V, Gifford CA, Donaghey J, Galonska C, Pop R, Reyon D, Tsai SQ, Mallard W, Joung JK, Rinn JL, Gnirke A, Meissner A. Liao J, et al. Among authors: karnik r. Nat Genet. 2015 May;47(5):469-78. doi: 10.1038/ng.3258. Epub 2015 Mar 30. Nat Genet. 2015. PMID: 25822089 Free PMC article.
DNA methylation dynamics of the human preimplantation embryo.
Smith ZD, Chan MM, Humm KC, Karnik R, Mekhoubad S, Regev A, Eggan K, Meissner A. Smith ZD, et al. Among authors: karnik r. Nature. 2014 Jul 31;511(7511):611-5. doi: 10.1038/nature13581. Epub 2014 Jul 23. Nature. 2014. PMID: 25079558 Free PMC article.
Genetic determinants and epigenetic effects of pioneer-factor occupancy.
Donaghey J, Thakurela S, Charlton J, Chen JS, Smith ZD, Gu H, Pop R, Clement K, Stamenova EK, Karnik R, Kelley DR, Gifford CA, Cacchiarelli D, Rinn JL, Gnirke A, Ziller MJ, Meissner A. Donaghey J, et al. Among authors: karnik r. Nat Genet. 2018 Feb;50(2):250-258. doi: 10.1038/s41588-017-0034-3. Epub 2018 Jan 22. Nat Genet. 2018. PMID: 29358654 Free PMC article.
LKB1 loss links serine metabolism to DNA methylation and tumorigenesis.
Kottakis F, Nicolay BN, Roumane A, Karnik R, Gu H, Nagle JM, Boukhali M, Hayward MC, Li YY, Chen T, Liesa M, Hammerman PS, Wong KK, Hayes DN, Shirihai OS, Dyson NJ, Haas W, Meissner A, Bardeesy N. Kottakis F, et al. Among authors: karnik r. Nature. 2016 Nov 17;539(7629):390-395. doi: 10.1038/nature20132. Epub 2016 Oct 31. Nature. 2016. PMID: 27799657 Free PMC article.
PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells.
Das PP, Hendrix DA, Apostolou E, Buchner AH, Canver MC, Beyaz S, Ljuboja D, Kuintzle R, Kim W, Karnik R, Shao Z, Xie H, Xu J, De Los Angeles A, Zhang Y, Choe J, Jun DL, Shen X, Gregory RI, Daley GQ, Meissner A, Kellis M, Hochedlinger K, Kim J, Orkin SH. Das PP, et al. Among authors: karnik r. Cell Rep. 2015 Sep 1;12(9):1456-70. doi: 10.1016/j.celrep.2015.07.053. Epub 2015 Aug 20. Cell Rep. 2015. PMID: 26299972 Free PMC article.
Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2.
Rajavelu A, Lungu C, Emperle M, Dukatz M, Bröhm A, Broche J, Hanelt I, Parsa E, Schiffers S, Karnik R, Meissner A, Carell T, Rathert P, Jurkowska RZ, Jeltsch A. Rajavelu A, et al. Among authors: karnik r. Nucleic Acids Res. 2018 Sep 28;46(17):9044-9056. doi: 10.1093/nar/gky715. Nucleic Acids Res. 2018. PMID: 30102379 Free PMC article.
Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency.
Cacchiarelli D, Trapnell C, Ziller MJ, Soumillon M, Cesana M, Karnik R, Donaghey J, Smith ZD, Ratanasirintrawoot S, Zhang X, Ho Sui SJ, Wu Z, Akopian V, Gifford CA, Doench J, Rinn JL, Daley GQ, Meissner A, Lander ES, Mikkelsen TS. Cacchiarelli D, et al. Among authors: karnik r. Cell. 2015 Jul 16;162(2):412-424. doi: 10.1016/j.cell.2015.06.016. Cell. 2015. PMID: 26186193 Free PMC article.
233 results