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The Anti-amyloid Compound DO1 Decreases Plaque Pathology and Neuroinflammation-Related Expression Changes in 5xFAD Transgenic Mice.
Boeddrich A, Babila JT, Wiglenda T, Diez L, Jacob M, Nietfeld W, Huska MR, Haenig C, Groenke N, Buntru A, Blanc E, Meier JC, Vannoni E, Erck C, Friedrich B, Martens H, Neuendorf N, Schnoegl S, Wolfer DP, Loos M, Beule D, Andrade-Navarro MA, Wanker EE. Boeddrich A, et al. Cell Chem Biol. 2019 Jan 17;26(1):109-120.e7. doi: 10.1016/j.chembiol.2018.10.013. Epub 2018 Nov 21. Cell Chem Biol. 2019. PMID: 30472115 Free article.
Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay.
Heiser V, Engemann S, Bröcker W, Dunkel I, Boeddrich A, Waelter S, Nordhoff E, Lurz R, Schugardt N, Rautenberg S, Herhaus C, Barnickel G, Böttcher H, Lehrach H, Wanker EE. Heiser V, et al. Among authors: boeddrich a. Proc Natl Acad Sci U S A. 2002 Dec 10;99 Suppl 4(Suppl 4):16400-6. doi: 10.1073/pnas.182426599. Epub 2002 Aug 28. Proc Natl Acad Sci U S A. 2002. PMID: 12200548 Free PMC article.
Small-molecule conversion of toxic oligomers to nontoxic β-sheet-rich amyloid fibrils.
Bieschke J, Herbst M, Wiglenda T, Friedrich RP, Boeddrich A, Schiele F, Kleckers D, Lopez del Amo JM, Grüning BA, Wang Q, Schmidt MR, Lurz R, Anwyl R, Schnoegl S, Fändrich M, Frank RF, Reif B, Günther S, Walsh DM, Wanker EE. Bieschke J, et al. Among authors: boeddrich a. Nat Chem Biol. 2011 Nov 20;8(1):93-101. doi: 10.1038/nchembio.719. Nat Chem Biol. 2011. PMID: 22101602
Systematic interaction network filtering identifies CRMP1 as a novel suppressor of huntingtin misfolding and neurotoxicity.
Stroedicke M, Bounab Y, Strempel N, Klockmeier K, Yigit S, Friedrich RP, Chaurasia G, Li S, Hesse F, Riechers SP, Russ J, Nicoletti C, Boeddrich A, Wiglenda T, Haenig C, Schnoegl S, Fournier D, Graham RK, Hayden MR, Sigrist S, Bates GP, Priller J, Andrade-Navarro MA, Futschik ME, Wanker EE. Stroedicke M, et al. Among authors: boeddrich a. Genome Res. 2015 May;25(5):701-13. doi: 10.1101/gr.182444.114. Genome Res. 2015. PMID: 25908449 Free PMC article.
Optimization of the All-D Peptide D3 for Aβ Oligomer Elimination.
Klein AN, Ziehm T, Tusche M, Buitenhuis J, Bartnik D, Boeddrich A, Wiglenda T, Wanker E, Funke SA, Brener O, Gremer L, Kutzsche J, Willbold D. Klein AN, et al. Among authors: boeddrich a. PLoS One. 2016 Apr 22;11(4):e0153035. doi: 10.1371/journal.pone.0153035. eCollection 2016. PLoS One. 2016. PMID: 27105346 Free PMC article.
18 results