Ysselstein D - Search Results

1

Synaptic, Mitochondrial, and Lysosomal Dysfunction in Parkinson's Disease.

Nguyen M, Wong YC, Ysselstein D, Severino A, Krainc D. Nguyen M, et al. Among authors: ysselstein d. Trends Neurosci. 2019 Feb;42(2):140-149. doi: 10.1016/j.tins.2018.11.001. Epub 2018 Nov 30. Trends Neurosci. 2019. PMID: 30509690 Free PMC article. Review.

2

Functional assays for the assessment of the pathogenicity of variants of GOSR2, an ER-to-Golgi SNARE involved in progressive myoclonus epilepsies.

Völker JM, Dergai M, Abriata LA, Mingard Y, Ysselstein D, Krainc D, Dal Peraro M, Fischer von Mollard G, Fasshauer D, Koliwer J, Schwake M. Völker JM, et al. Among authors: ysselstein d. Dis Model Mech. 2017 Dec 19;10(12):1391-1398. doi: 10.1242/dmm.029132. Dis Model Mech. 2017. PMID: 28982678 Free PMC article.

3

Lysosomal integral membrane protein-2 as a phospholipid receptor revealed by biophysical and cellular studies.

Conrad KS, Cheng TW, Ysselstein D, Heybrock S, Hoth LR, Chrunyk BA, Am Ende CW, Krainc D, Schwake M, Saftig P, Liu S, Qiu X, Ehlers MD. Conrad KS, et al. Among authors: ysselstein d. Nat Commun. 2017 Dec 4;8(1):1908. doi: 10.1038/s41467-017-02044-8. Nat Commun. 2017. PMID: 29199275 Free PMC article.

4

Mitochondria-lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis.

Wong YC, Ysselstein D, Krainc D. Wong YC, et al. Among authors: ysselstein d. Nature. 2018 Feb 15;554(7692):382-386. doi: 10.1038/nature25486. Epub 2018 Jan 24. Nature. 2018. PMID: 29364868 Free PMC article.

5

β-Glucocerebrosidase Modulators Promote Dimerization of β-Glucocerebrosidase and Reveal an Allosteric Binding Site.

Zheng J, Chen L, Skinner OS, Ysselstein D, Remis J, Lansbury P, Skerlj R, Mrosek M, Heunisch U, Krapp S, Charrow J, Schwake M, Kelleher NL, Silverman RB, Krainc D. Zheng J, et al. Among authors: ysselstein d. J Am Chem Soc. 2018 May 9;140(18):5914-5924. doi: 10.1021/jacs.7b13003. Epub 2018 Apr 30. J Am Chem Soc. 2018. PMID: 29676907 Free PMC article.

6

Untangling alpha synuclein fibrils by graphene quantum dots.

Ysselstein D, Krainc D. Ysselstein D, et al. Mov Disord. 2018 Nov;33(11):1673. doi: 10.1002/mds.27511. Mov Disord. 2018. PMID: 30485906 Free PMC article. No abstract available.

7

Conversion of Quinazoline Modulators from Inhibitors to Activators of β-Glucocerebrosidase.

Zheng J, Jeon S, Jiang W, Burbulla LF, Ysselstein D, Oevel K, Krainc D, Silverman RB. Zheng J, et al. Among authors: ysselstein d. J Med Chem. 2019 Feb 14;62(3):1218-1230. doi: 10.1021/acs.jmedchem.8b01294. Epub 2019 Jan 15. J Med Chem. 2019. PMID: 30645117 Free PMC article.

8

Fluctuations in cell density alter protein markers of multiple cellular compartments, confounding experimental outcomes.

Trajkovic K, Valdez C, Ysselstein D, Krainc D. Trajkovic K, et al. Among authors: ysselstein d. PLoS One. 2019 Feb 4;14(2):e0211727. doi: 10.1371/journal.pone.0211727. eCollection 2019. PLoS One. 2019. PMID: 30716115 Free PMC article.

9

Emerging links between pediatric lysosomal storage diseases and adult parkinsonism.

Ysselstein D, Shulman JM, Krainc D. Ysselstein D, et al. Mov Disord. 2019 May;34(5):614-624. doi: 10.1002/mds.27631. Epub 2019 Feb 6. Mov Disord. 2019. PMID: 30726573 Free PMC article.

10

Correction to Conversion of Quinazoline Modulators from Inhibitors to Activators of β-Glucocerebrosidase.

Zheng J, Jeon S, Jiang W, Burbulla LF, Ysselstein D, Oevel K, Krainc D, Silverman RB. Zheng J, et al. Among authors: ysselstein d. J Med Chem. 2019 Mar 14;62(5):2850. doi: 10.1021/acs.jmedchem.9b00284. Epub 2019 Feb 22. J Med Chem. 2019. PMID: 30793892 No abstract available.

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