Kelley MR - Search Results

1

Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis.

Cai Z, Kotzin JJ, Ramdas B, Chen S, Nelanuthala S, Palam LR, Pandey R, Mali RS, Liu Y, Kelley MR, Sandusky G, Mohseni M, Williams A, Henao-Mejia J, Kapur R. Cai Z, et al. Among authors: kelley mr. Cell Stem Cell. 2018 Dec 6;23(6):833-849.e5. doi: 10.1016/j.stem.2018.10.013. Cell Stem Cell. 2018. PMID: 30526882 Free PMC article.

2

Reversal of 1,3-bis(2-chloroethyl)-1-nitrosourea-induced severe immunodeficiency by transduction of murine long-lived hemopoietic progenitor cells using O6-methylguanine DNA methyltransferase complementary DNA.

Maze R, Kapur R, Kelley MR, Hansen WK, Oh SY, Williams DA. Maze R, et al. Among authors: kelley mr. J Immunol. 1997 Jan 15;158(2):1006-13. J Immunol. 1997. PMID: 8993023

3

Reduced expression of DNA repair and redox signaling protein APE1/Ref-1 impairs human pancreatic cancer cell survival, proliferation, and cell cycle progression.

Jiang Y, Zhou S, Sandusky GE, Kelley MR, Fishel ML. Jiang Y, et al. Among authors: kelley mr. Cancer Invest. 2010 Nov;28(9):885-95. doi: 10.3109/07357907.2010.512816. Cancer Invest. 2010. PMID: 20919954 Free PMC article.

4

Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival.

Logsdon DP, Shah F, Carta F, Supuran CT, Kamocka M, Jacobsen MH, Sandusky GE, Kelley MR, Fishel ML. Logsdon DP, et al. Among authors: kelley mr. Sci Rep. 2018 Sep 13;8(1):13759. doi: 10.1038/s41598-018-32034-9. Sci Rep. 2018. PMID: 30214007 Free PMC article.

5

Antitumor Activity and Mechanistic Characterization of APE1/Ref-1 Inhibitors in Bladder Cancer.

Fishel ML, Xia H, McGeown J, McIlwain DW, Elbanna M, Craft AA, Kaimakliotis HZ, Sandusky GE, Zhang C, Pili R, Kelley MR, Jerde TJ. Fishel ML, et al. Among authors: kelley mr. Mol Cancer Ther. 2019 Nov;18(11):1947-1960. doi: 10.1158/1535-7163.MCT-18-1166. Epub 2019 Aug 14. Mol Cancer Ther. 2019. PMID: 31413178 Free PMC article.

6

Ref-1 redox activity alters cancer cell metabolism in pancreatic cancer: exploiting this novel finding as a potential target.

Gampala S, Shah F, Lu X, Moon HR, Babb O, Umesh Ganesh N, Sandusky G, Hulsey E, Armstrong L, Mosely AL, Han B, Ivan M, Yeh JJ, Kelley MR, Zhang C, Fishel ML. Gampala S, et al. Among authors: kelley mr. J Exp Clin Cancer Res. 2021 Aug 10;40(1):251. doi: 10.1186/s13046-021-02046-x. J Exp Clin Cancer Res. 2021. PMID: 34376225 Free PMC article.

7

Combined heterozygosity of FLT3 ITD, TET2, and DNMT3A results in aggressive leukemia.

Ramdas B, Lakshmi Reddy P, Mali RS, Pasupuleti SK, Zhang J, Kelley MR, Paczesny S, Zhang C, Kapur R. Ramdas B, et al. Among authors: kelley mr. JCI Insight. 2022 Sep 8;7(17):e162016. doi: 10.1172/jci.insight.162016. JCI Insight. 2022. PMID: 36073548 Free PMC article.

8

The myeloid zinc finger gene (MZF-1) delays retinoic acid-induced apoptosis and differentiation in myeloid leukemia cells.

Robertson KA, Hill DP, Kelley MR, Tritt R, Crum B, Van Epps S, Srour E, Rice S, Hromas R. Robertson KA, et al. Among authors: kelley mr. Leukemia. 1998 May;12(5):690-8. doi: 10.1038/sj.leu.2401005. Leukemia. 1998. PMID: 9593266

9

Ape1 regulates hematopoietic differentiation of embryonic stem cells through its redox functional domain.

Zou GM, Luo MH, Reed A, Kelley MR, Yoder MC. Zou GM, et al. Among authors: kelley mr. Blood. 2007 Mar 1;109(5):1917-22. doi: 10.1182/blood-2006-08-044172. Epub 2006 Oct 19. Blood. 2007. PMID: 17053053 Free article.

10

Inhibition of the redox function of APE1/Ref-1 in myeloid leukemia cell lines results in a hypersensitive response to retinoic acid-induced differentiation and apoptosis.

Fishel ML, Colvin ES, Luo M, Kelley MR, Robertson KA. Fishel ML, et al. Among authors: kelley mr. Exp Hematol. 2010 Dec;38(12):1178-88. doi: 10.1016/j.exphem.2010.08.011. Epub 2010 Sep 6. Exp Hematol. 2010. PMID: 20826193 Free PMC article.

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