Schülein R - Search Results

1

Use of a sequential high throughput screening assay to identify novel inhibitors of the eukaryotic SRP-Sec61 targeting/translocation pathway.

Klein W, Rutz C, Eckhard J, Provinciael B, Specker E, Neuenschwander M, Kleinau G, Scheerer P, von Kries JP, Nazaré M, Vermeire K, Schülein R. Klein W, et al. Among authors: schulein r. PLoS One. 2018 Dec 13;13(12):e0208641. doi: 10.1371/journal.pone.0208641. eCollection 2018. PLoS One. 2018. PMID: 30543669 Free PMC article.

2

Inhibitors of the Sec61 Complex and Novel High Throughput Screening Strategies to Target the Protein Translocation Pathway.

Pauwels E, Schülein R, Vermeire K. Pauwels E, et al. Among authors: schulein r. Int J Mol Sci. 2021 Nov 5;22(21):12007. doi: 10.3390/ijms222112007. Int J Mol Sci. 2021. PMID: 34769437 Free PMC article. Review.

3

The sequence after the signal peptide of the G protein-coupled endothelin B receptor is required for efficient translocon gating at the endoplasmic reticulum membrane.

Alken M, Schmidt A, Rutz C, Furkert J, Kleinau G, Rosenthal W, Schülein R. Alken M, et al. Among authors: schulein r. Mol Pharmacol. 2009 Apr;75(4):801-11. doi: 10.1124/mol.108.051581. Epub 2009 Jan 9. Mol Pharmacol. 2009. PMID: 19136571

4

N-Terminal Signal Peptides of G Protein-Coupled Receptors: Significance for Receptor Biosynthesis, Trafficking, and Signal Transduction.

Rutz C, Klein W, Schülein R. Rutz C, et al. Among authors: schulein r. Prog Mol Biol Transl Sci. 2015;132:267-87. doi: 10.1016/bs.pmbts.2015.03.003. Epub 2015 Apr 11. Prog Mol Biol Transl Sci. 2015. PMID: 26055063 Review.

5

A Proteomic Study on the Membrane Protein Fraction of T Cells Confirms High Substrate Selectivity for the ER Translocation Inhibitor Cyclotriazadisulfonamide.

Pauwels E, Rutz C, Provinciael B, Stroobants J, Schols D, Hartmann E, Krause E, Stephanowitz H, Schülein R, Vermeire K. Pauwels E, et al. Among authors: schulein r. Mol Cell Proteomics. 2021;20:100144. doi: 10.1016/j.mcpro.2021.100144. Epub 2021 Sep 2. Mol Cell Proteomics. 2021. PMID: 34481949 Free PMC article.

6

Defining a conformational consensus motif in cotransin-sensitive signal sequences: a proteomic and site-directed mutagenesis study.

Klein W, Westendorf C, Schmidt A, Conill-Cortés M, Rutz C, Blohs M, Beyermann M, Protze J, Krause G, Krause E, Schülein R. Klein W, et al. Among authors: schulein r. PLoS One. 2015 Mar 25;10(3):e0120886. doi: 10.1371/journal.pone.0120886. eCollection 2015. PLoS One. 2015. PMID: 25806945 Free PMC article.

7

Functional Significance of the Signal Peptides of Corticotropin-Releasing Factor Receptors.

Schulein R, Gibert A, Rutz C. Schulein R, et al. Curr Mol Pharmacol. 2017;10(4):311-317. doi: 10.2174/1874467210666170224094915. Curr Mol Pharmacol. 2017. PMID: 28240192 Review.

8

A New Highly Thyrotropin Receptor-Selective Small-Molecule Antagonist with Potential for the Treatment of Graves' Orbitopathy.

Marcinkowski P, Hoyer I, Specker E, Furkert J, Rutz C, Neuenschwander M, Sobottka S, Sun H, Nazare M, Berchner-Pfannschmidt U, von Kries JP, Eckstein A, Schülein R, Krause G. Marcinkowski P, et al. Among authors: schulein r. Thyroid. 2019 Jan;29(1):111-123. doi: 10.1089/thy.2018.0349. Epub 2018 Dec 15. Thyroid. 2019. PMID: 30351237

9

The specific monomer/dimer equilibrium of the corticotropin-releasing factor receptor type 1 is established in the endoplasmic reticulum.

Teichmann A, Gibert A, Lampe A, Grzesik P, Rutz C, Furkert J, Schmoranzer J, Krause G, Wiesner B, Schülein R. Teichmann A, et al. Among authors: schulein r. J Biol Chem. 2014 Aug 29;289(35):24250-62. doi: 10.1074/jbc.M114.553644. Epub 2014 Jun 25. J Biol Chem. 2014. PMID: 24966326 Free PMC article.

10

The signal peptide of the G protein-coupled human endothelin B receptor is necessary for translocation of the N-terminal tail across the endoplasmic reticulum membrane.

Köchl R, Alken M, Rutz C, Krause G, Oksche A, Rosenthal W, Schülein R. Köchl R, et al. Among authors: schulein r. J Biol Chem. 2002 May 3;277(18):16131-8. doi: 10.1074/jbc.M111674200. Epub 2002 Feb 19. J Biol Chem. 2002. PMID: 11854280 Free article.

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