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Activating mutations in the MAP-kinase pathway define non-ossifying fibroma of bone.
Baumhoer D, Kovac M, Sperveslage J, Ameline B, Strobl AC, Krause A, Trautmann M, Wardelmann E, Nathrath M, Höller S, Hardes J, Gosheger G, Krieg AH, Vieth V, Tirabosco R, Amary F, Flanagan AM, Hartmann W. Baumhoer D, et al. Among authors: kovac m. J Pathol. 2019 May;248(1):116-122. doi: 10.1002/path.5216. Epub 2019 Jan 24. J Pathol. 2019. PMID: 30549028
NTRK fusions in osteosarcoma are rare and non-functional events.
Ameline B, Saba KH, Kovac M, Magnusson L, Witt O, Bielack S, Nathrath M, Nord KH, Baumhoer D. Ameline B, et al. Among authors: kovac m. J Pathol Clin Res. 2020 Apr;6(2):107-112. doi: 10.1002/cjp2.158. Epub 2020 Feb 5. J Pathol Clin Res. 2020. PMID: 32022484 Free PMC article.
GNAS mutations are not detected in parosteal and low-grade central osteosarcomas.
Salinas-Souza C, De Andrea C, Bihl M, Kovac M, Pillay N, Forshew T, Gutteridge A, Ye H, Amary MF, Tirabosco R, Toledo SR, Baumhoer D, Flanagan AM. Salinas-Souza C, et al. Among authors: kovac m. Mod Pathol. 2015 Oct;28(10):1336-42. doi: 10.1038/modpathol.2015.91. Epub 2015 Aug 7. Mod Pathol. 2015. PMID: 26248895 Free article.
Germline RET variants underlie a subset of paediatric osteosarcoma.
Kovac M, Woolley C, Ribi S, Blattmann C, Roth E, Morini M, Kovacova M, Ameline B, Kulozik A, Bielack S, Hartmann W, Ballinger ML, Thomas DM, Tomlinson I, Nathrath M, Heinimann K, Baumhoer D. Kovac M, et al. J Med Genet. 2021 Jan;58(1):20-24. doi: 10.1136/jmedgenet-2019-106734. Epub 2020 Mar 16. J Med Genet. 2021. PMID: 32179705
Loss of NF2 defines a genetic subgroup of non-FOS-rearranged osteoblastoma.
Saba KH, Cornmark L, Hofvander J, Magnusson L, Nilsson J, van den Bos H, Spierings DC, Foijer F, Staaf J, Brosjö O, Sumathi VP, Lam SW, Szuhai K, Bovée JV, Kovac M, Baumhoer D, Styring E, Nord KH. Saba KH, et al. Among authors: kovac m. J Pathol Clin Res. 2020 Oct;6(4):231-237. doi: 10.1002/cjp2.172. Epub 2020 Jun 16. J Pathol Clin Res. 2020. PMID: 32542935 Free PMC article.
665 results