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Activating mutations in the MAP-kinase pathway define non-ossifying fibroma of bone.
Baumhoer D, Kovac M, Sperveslage J, Ameline B, Strobl AC, Krause A, Trautmann M, Wardelmann E, Nathrath M, Höller S, Hardes J, Gosheger G, Krieg AH, Vieth V, Tirabosco R, Amary F, Flanagan AM, Hartmann W. Baumhoer D, et al. Among authors: strobl ac. J Pathol. 2019 May;248(1):116-122. doi: 10.1002/path.5216. Epub 2019 Jan 24. J Pathol. 2019. PMID: 30549028
Drivers underpinning the malignant transformation of giant cell tumour of bone.
Fittall MW, Lyskjaer I, Ellery P, Lombard P, Ijaz J, Strobl AC, Oukrif D, Tarabichi M, Sill M, Koelsche C, Mechtersheimer G, Demeulemeester J, Tirabosco R, Amary F, Campbell PJ, Pfister SM, Jones DT, Pillay N, Van Loo P, Behjati S, Flanagan AM. Fittall MW, et al. Among authors: strobl ac. J Pathol. 2020 Dec;252(4):433-440. doi: 10.1002/path.5537. Epub 2020 Oct 6. J Pathol. 2020. PMID: 32866294 Free PMC article.
Recurrent rearrangements of FOS and FOSB define osteoblastoma.
Fittall MW, Mifsud W, Pillay N, Ye H, Strobl AC, Verfaillie A, Demeulemeester J, Zhang L, Berisha F, Tarabichi M, Young MD, Miranda E, Tarpey PS, Tirabosco R, Amary F, Grigoriadis AE, Stratton MR, Van Loo P, Antonescu CR, Campbell PJ, Flanagan AM, Behjati S. Fittall MW, et al. Among authors: strobl ac. Nat Commun. 2018 Jun 1;9(1):2150. doi: 10.1038/s41467-018-04530-z. Nat Commun. 2018. PMID: 29858576 Free PMC article.
Synovial chondromatosis and soft tissue chondroma: extraosseous cartilaginous tumor defined by FN1 gene rearrangement.
Amary F, Perez-Casanova L, Ye H, Cottone L, Strobl AC, Cool P, Miranda E, Berisha F, Aston W, Rocha M, O'Donnell P, Pillay N, Tirabosco R, Baumhoer D, Hookway ES, Flanagan AM. Amary F, et al. Among authors: strobl ac. Mod Pathol. 2019 Dec;32(12):1762-1771. doi: 10.1038/s41379-019-0315-8. Epub 2019 Jul 4. Mod Pathol. 2019. PMID: 31273315 Free PMC article.
Sarcoma and the 100,000 Genomes Project: our experience and changes to practice.
Prendergast SC, Strobl AC, Cross W, Pillay N, Strauss SJ, Ye H, Lindsay D, Tirabosco R, Chalker J, Mahamdallie SS, Sosinsky A; RNOH Pathology Laboratory and Biobank Team; Genomics England Research Consortium; Flanagan AM, Amary F. Prendergast SC, et al. Among authors: strobl ac. J Pathol Clin Res. 2020 Oct;6(4):297-307. doi: 10.1002/cjp2.174. Epub 2020 Jun 23. J Pathol Clin Res. 2020. PMID: 32573957 Free PMC article.
A genetic model for central chondrosarcoma evolution correlates with patient outcome.
Cross W, Lyskjær I, Lesluyes T, Hargreaves S, Strobl AC, Davies C, Waise S, Hames-Fathi S, Oukrif D, Ye H, Amary F, Tirabosco R, Gerrand C, Baker T, Barnes D, Steele C, Alexandrov L, Bond G; Genomics England Research Consortium; Cool P, Pillay N, Van Loo P, Flanagan AM. Cross W, et al. Among authors: strobl ac. Genome Med. 2022 Aug 30;14(1):99. doi: 10.1186/s13073-022-01084-0. Genome Med. 2022. PMID: 36042521 Free PMC article.
Circulating tumour DNA is a promising biomarker for risk stratification of central chondrosarcoma with IDH1/2 and GNAS mutations.
Lyskjaer I, Davies C, Strobl AC, Hindley J, James S, Lalam RK, Cross W, Hide G, Rankin KS, Jeys L, Tirabosco R, Stevenson J; Genomics England Research Consortium; O'Donnell P, Cool P, Flanagan AM. Lyskjaer I, et al. Among authors: strobl ac. Mol Oncol. 2021 Dec;15(12):3679-3690. doi: 10.1002/1878-0261.13102. Epub 2021 Sep 30. Mol Oncol. 2021. PMID: 34528398 Free PMC article.
Osteosarcoma: Novel prognostic biomarkers using circulating and cell-free tumour DNA.
Lyskjær I, Kara N, De Noon S, Davies C, Rocha AM, Strobl AC, Usher I, Gerrand C, Strauss SJ, Schrimpf D, von Deimling A, Beck S, Flanagan AM. Lyskjær I, et al. Among authors: strobl ac. Eur J Cancer. 2022 Jun;168:1-11. doi: 10.1016/j.ejca.2022.03.002. Epub 2022 Apr 14. Eur J Cancer. 2022. PMID: 35421838 Free article.
13 results