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Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.
Shrine N, Portelli MA, John C, Soler Artigas M, Bennett N, Hall R, Lewis J, Henry AP, Billington CK, Ahmad A, Packer RJ, Shaw D, Pogson ZEK, Fogarty A, McKeever TM, Singapuri A, Heaney LG, Mansur AH, Chaudhuri R, Thomson NC, Holloway JW, Lockett GA, Howarth PH, Djukanovic R, Hankinson J, Niven R, Simpson A, Chung KF, Sterk PJ, Blakey JD, Adcock IM, Hu S, Guo Y, Obeidat M, Sin DD, van den Berge M, Nickle DC, Bossé Y, Tobin MD, Hall IP, Brightling CE, Wain LV, Sayers I. Shrine N, et al. Among authors: hu s. Lancet Respir Med. 2019 Jan;7(1):20-34. doi: 10.1016/S2213-2600(18)30389-8. Epub 2018 Dec 11. Lancet Respir Med. 2019. PMID: 30552067 Free PMC article.
Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study.
Loza MJ, Djukanovic R, Chung KF, Horowitz D, Ma K, Branigan P, Barnathan ES, Susulic VS, Silkoff PE, Sterk PJ, Baribaud F; ADEPT (Airways Disease Endotyping for Personalized Therapeutics) and U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease Outcome Consortium) investigators. Loza MJ, et al. Respir Res. 2016 Dec 15;17(1):165. doi: 10.1186/s12931-016-0482-9. Respir Res. 2016. PMID: 27978840 Free PMC article.
Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study.
Reinke SN, Naz S, Chaleckis R, Gallart-Ayala H, Kolmert J, Kermani NZ, Tiotiu A, Broadhurst DI, Lundqvist A, Olsson H, Ström M, Wheelock ÅM, Gómez C, Ericsson M, Sousa AR, Riley JH, Bates S, Scholfield J, Loza M, Baribaud F, Bakke PS, Caruso M, Chanez P, Fowler SJ, Geiser T, Howarth P, Horváth I, Krug N, Montuschi P, Behndig A, Singer F, Musial J, Shaw DE, Dahlén B, Hu S, Lasky-Su J, Sterk PJ, Chung KF, Djukanovic R, Dahlén SE, Adcock IM, Wheelock CE; U-BIOPRED Study Group. Reinke SN, et al. Among authors: hu s. Eur Respir J. 2022 Jun 30;59(6):2101733. doi: 10.1183/13993003.01733-2021. Print 2022 Jun. Eur Respir J. 2022. PMID: 34824054 Free PMC article.
Clinical and transcriptomic features of persistent exacerbation-prone severe asthma in U-BIOPRED cohort.
Hoda U, Pavlidis S, Bansal AT, Takahashi K, Hu S, Ng Kee Kwong F, Rossios C, Sun K, Bhavsar P, Loza M, Baribaud F, Chanez P, Fowler SJ, Horvath I, Montuschi P, Singer F, Musial J, Dahlen B, Krug N, Sandstrom T, Shaw DE, Lutter R, Fleming LJ, Howarth PH, Caruso M, Sousa AR, Corfield J, Auffray C, De Meulder B, Lefaudeux D, Dahlen SE, Djukanovic R, Sterk PJ, Guo Y, Adcock IM, Chung KF; U-BIOPRED study group. Hoda U, et al. Among authors: hu s. Clin Transl Med. 2022 Apr;12(4):e816. doi: 10.1002/ctm2.816. Clin Transl Med. 2022. PMID: 35474304 Free PMC article.
U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics.
Lefaudeux D, De Meulder B, Loza MJ, Peffer N, Rowe A, Baribaud F, Bansal AT, Lutter R, Sousa AR, Corfield J, Pandis I, Bakke PS, Caruso M, Chanez P, Dahlén SE, Fleming LJ, Fowler SJ, Horvath I, Krug N, Montuschi P, Sanak M, Sandstrom T, Shaw DE, Singer F, Sterk PJ, Roberts G, Adcock IM, Djukanovic R, Auffray C, Chung KF; U-BIOPRED Study Group. Lefaudeux D, et al. J Allergy Clin Immunol. 2017 Jun;139(6):1797-1807. doi: 10.1016/j.jaci.2016.08.048. Epub 2016 Oct 20. J Allergy Clin Immunol. 2017. PMID: 27773852 Free article.
Genome-Wide Association Study of Korean Asthmatics: A Comparison With UK Asthmatics.
An J, Do AR, Kang HY, Kim WJ, Lee S, Lee JH, Song WJ, Kwon HS, Cho YS, Moon HB, Hu S, Adcock IM, Chung KF, Won S, Kim TB. An J, et al. Among authors: hu s. Allergy Asthma Immunol Res. 2021 Jul;13(4):609-622. doi: 10.4168/aair.2021.13.4.609. Allergy Asthma Immunol Res. 2021. PMID: 34212547 Free PMC article.
Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux.
Perotin JM, Schofield JPR, Wilson SJ, Ward J, Brandsma J, Strazzeri F, Bansal A, Yang X, Rowe A, Corfield J, Lutter R, Shaw DE, Bakke PS, Caruso M, Dahlén B, Fowler SJ, Horváth I, Howarth P, Krug N, Montuschi P, Sanak M, Sandström T, Sun K, Pandis I, Auffray C, De Meulder B, Lefaudeux D, Riley JH, Sousa AR, Dahlen SE, Adcock IM, Chung KF, Sterk PJ, Skipp PJ, Collins JE, Davies DE, Djukanović R; U-BIOPRED Study Group; U-BIOPRED:. Perotin JM, et al. Eur Respir J. 2019 Jun 27;53(6):1900453. doi: 10.1183/13993003.00453-2019. Print 2019 Jun. Eur Respir J. 2019. PMID: 31023846 Free PMC article. No abstract available.
Determinants of expression of SARS-CoV-2 entry-related genes in upper and lower airways.
Aliee H, Massip F, Qi C, Stella de Biase M, van Nijnatten J, Kersten ETG, Kermani NZ, Khuder B, Vonk JM, Vermeulen RCH; U-BIOPRED study group; Cambridge Lung Cancer Early Detection Programme; INER-Ciencias Mexican Lung Program; Neighbors M, Tew GW, Grimbaldeston MA, Ten Hacken NHT, Hu S, Guo Y, Zhang X, Sun K, Hiemstra PS, Ponder BA, Mäkelä MJ, Malmström K, Rintoul RC, Reyfman PA, Theis FJ, Brandsma CA, Adcock IM, Timens W, Xu CJ, van den Berge M, Schwarz RF, Koppelman GH, Nawijn MC, Faiz A. Aliee H, et al. Among authors: hu s. Allergy. 2022 Feb;77(2):690-694. doi: 10.1111/all.15152. Epub 2021 Nov 3. Allergy. 2022. PMID: 34698405 Free PMC article. No abstract available.
Determinants of SARS-CoV-2 receptor gene expression in upper and lower airways.
Aliee H, Massip F, Qi C, de Biase MS, van Nijnatten J, Kersten ETG, Kermani NZ, Khuder B, Vonk JM, Vermeulen RCH; U-BIOPRED study group; Cambridge Lung Cancer Early Detection Programme; INER-Ciencias Mexican Lung Program; NHLBI LungMAP Consortium; Neighbors M, Tew GW, Grimbaldeston M, Ten Hacken NHT, Hu S, Guo Y, Zhang X, Sun K, Hiemstra PS, Ponder BA, Mäkelä MJ, Malmström K, Rintoul RC, Reyfman PA, Theis FJ, Brandsma CA, Adcock IM, Timens W, Xu CJ, van den Berge M, Schwarz RF, Koppelman GH, Nawijn MC, Faiz A. Aliee H, et al. Among authors: hu s. medRxiv [Preprint]. 2020 Sep 2:2020.08.31.20169946. doi: 10.1101/2020.08.31.20169946. medRxiv. 2020. PMID: 32909007 Free PMC article. Updated. Preprint.
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