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Page 1
Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.
Shrine N, Portelli MA, John C, Soler Artigas M, Bennett N, Hall R, Lewis J, Henry AP, Billington CK, Ahmad A, Packer RJ, Shaw D, Pogson ZEK, Fogarty A, McKeever TM, Singapuri A, Heaney LG, Mansur AH, Chaudhuri R, Thomson NC, Holloway JW, Lockett GA, Howarth PH, Djukanovic R, Hankinson J, Niven R, Simpson A, Chung KF, Sterk PJ, Blakey JD, Adcock IM, Hu S, Guo Y, Obeidat M, Sin DD, van den Berge M, Nickle DC, Bossé Y, Tobin MD, Hall IP, Brightling CE, Wain LV, Sayers I. Shrine N, et al. Among authors: thomson nc. Lancet Respir Med. 2019 Jan;7(1):20-34. doi: 10.1016/S2213-2600(18)30389-8. Epub 2018 Dec 11. Lancet Respir Med. 2019. PMID: 30552067 Free PMC article.
Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank.
Wain LV, Shrine N, Miller S, Jackson VE, Ntalla I, Soler Artigas M, Billington CK, Kheirallah AK, Allen R, Cook JP, Probert K, Obeidat M, Bossé Y, Hao K, Postma DS, Paré PD, Ramasamy A; UK Brain Expression Consortium (UKBEC); Mägi R, Mihailov E, Reinmaa E, Melén E, O'Connell J, Frangou E, Delaneau O; OxGSK Consortium; Freeman C, Petkova D, McCarthy M, Sayers I, Deloukas P, Hubbard R, Pavord I, Hansell AL, Thomson NC, Zeggini E, Morris AP, Marchini J, Strachan DP, Tobin MD, Hall IP. Wain LV, et al. Among authors: thomson nc. Lancet Respir Med. 2015 Oct;3(10):769-81. doi: 10.1016/S2213-2600(15)00283-0. Epub 2015 Sep 27. Lancet Respir Med. 2015. PMID: 26423011 Free PMC article.
Effects of older age and age of asthma onset on clinical and inflammatory variables in severe refractory asthma.
Chaudhuri R, McSharry C, Heaney LG, Niven R, Brightling CE, Menzies-Gow AN, Bucknall C, Mansur AH, Lee W, Shepherd M, Spears M, Cowan DC, Husi H, Thomson NC; BTS Severe Asthma Network. Chaudhuri R, et al. Among authors: thomson nc. Respir Med. 2016 Sep;118:46-52. doi: 10.1016/j.rmed.2016.07.005. Epub 2016 Jul 9. Respir Med. 2016. PMID: 27578470 Free article.
Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium.
Portelli MA, Dijk FN, Ketelaar ME, Shrine N, Hankinson J, Bhaker S, Grotenboer NS, Obeidat M, Henry AP, Billington CK, Shaw D, Johnson SR, Pogson ZE, Fogarty A, McKeever TM, Nickle DC, Bossé Y, van den Berge M, Faiz A, Brouwer S, Vonk JM, de Vos P, Brandsma CA, Vermeulen CJ, Singapuri A, Heaney LG, Mansur AH, Chaudhuri R, Thomson NC, Holloway JW, Lockett GA, Howarth PH, Niven R, Simpson A, Blakey JD, Tobin MD, Postma DS, Hall IP, Wain LV, Nawijn MC, Brightling CE, Koppelman GH, Sayers I. Portelli MA, et al. Among authors: thomson nc. JCI Insight. 2020 Apr 23;5(8):e132446. doi: 10.1172/jci.insight.132446. JCI Insight. 2020. PMID: 32324168 Free PMC article.
Phenotypic and functional translation of IL33 genetics in asthma.
Ketelaar ME, Portelli MA, Dijk FN, Shrine N, Faiz A, Vermeulen CJ, Xu CJ, Hankinson J, Bhaker S, Henry AP, Billington CK, Shaw DE, Johnson SR, Benest AV, Pang V, Bates DO, Pogson ZEK, Fogarty A, McKeever TM, Singapuri A, Heaney LG, Mansur AH, Chaudhuri R, Thomson NC, Holloway JW, Lockett GA, Howarth PH, Niven R, Simpson A, Tobin MD, Hall IP, Wain LV, Blakey JD, Brightling CE, Obeidat M, Sin DD, Nickle DC, Bossé Y, Vonk JM, van den Berge M, Koppelman GH, Sayers I, Nawijn MC. Ketelaar ME, et al. Among authors: thomson nc. J Allergy Clin Immunol. 2021 Jan;147(1):144-157. doi: 10.1016/j.jaci.2020.04.051. Epub 2020 May 19. J Allergy Clin Immunol. 2021. PMID: 32442646
Asthma in smokers: challenges and opportunities.
Thomson NC, Chaudhuri R. Thomson NC, et al. Curr Opin Pulm Med. 2009 Jan;15(1):39-45. doi: 10.1097/MCP.0b013e32831da894. Curr Opin Pulm Med. 2009. PMID: 19077704 Review.
A large-scale, consortium-based genomewide association study of asthma.
Moffatt MF, Gut IG, Demenais F, Strachan DP, Bouzigon E, Heath S, von Mutius E, Farrall M, Lathrop M, Cookson WOCM; GABRIEL Consortium. Moffatt MF, et al. N Engl J Med. 2010 Sep 23;363(13):1211-1221. doi: 10.1056/NEJMoa0906312. N Engl J Med. 2010. PMID: 20860503 Free PMC article.
Emerging therapies for severe asthma.
Thomson NC, Chaudhuri R, Spears M. Thomson NC, et al. BMC Med. 2011 Sep 6;9:102. doi: 10.1186/1741-7015-9-102. BMC Med. 2011. PMID: 21896202 Free PMC article. Review.
Bronchial thermoplasty for severe asthma.
Thomson NC, Bicknell S, Chaudhuri R. Thomson NC, et al. Curr Opin Allergy Clin Immunol. 2012 Jun;12(3):241-8. doi: 10.1097/ACI.0b013e32835335ca. Curr Opin Allergy Clin Immunol. 2012. PMID: 22475996 Review.
Omalizumab: clinical use for the management of asthma.
Thomson NC, Chaudhuri R. Thomson NC, et al. Clin Med Insights Circ Respir Pulm Med. 2012;6:27-40. doi: 10.4137/CCRPM.S7793. Epub 2012 Jun 12. Clin Med Insights Circ Respir Pulm Med. 2012. PMID: 22745565 Free PMC article.
244 results