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Transmission of drug-resistant tuberculosis in HIV-endemic settings.
Khan PY, Yates TA, Osman M, Warren RM, van der Heijden Y, Padayatchi N, Nardell EA, Moore D, Mathema B, Gandhi N, Eldholm V, Dheda K, Hesseling AC, Mizrahi V, Rustomjee R, Pym A. Khan PY, et al. Among authors: pym a. Lancet Infect Dis. 2019 Mar;19(3):e77-e88. doi: 10.1016/S1473-3099(18)30537-1. Epub 2018 Dec 13. Lancet Infect Dis. 2019. PMID: 30554996 Free PMC article. Review.
Impact of tuberculosis treatment and antiretroviral therapy on serial RD-1-specific quantitative T-cell readouts (QuantiFERON-TB Gold In-Tube), and relationship to treatment-related outcomes and bacterial burden.
Mthiyane T, Rustomjee R, Pym A, Connolly C, Onyebujoh P, Theron G, Dheda K. Mthiyane T, et al. Among authors: pym a. Int J Infect Dis. 2015 Jul;36:46-53. doi: 10.1016/j.ijid.2015.05.006. Epub 2015 May 21. Int J Infect Dis. 2015. PMID: 26003404 Free article.
Bedaquiline resistance in drug-resistant tuberculosis HIV co-infected patients.
Nimmo C, Millard J, Brien K, Moodley S, van Dorp L, Lutchminarain K, Wolf A, Grant AD, Balloux F, Pym AS, Padayatchi N, O'Donnell M. Nimmo C, et al. Among authors: pym as. Eur Respir J. 2020 Jun 4;55(6):1902383. doi: 10.1183/13993003.02383-2019. Print 2020 Jun. Eur Respir J. 2020. PMID: 32060065 Free PMC article.
Population-level emergence of bedaquiline and clofazimine resistance-associated variants among patients with drug-resistant tuberculosis in southern Africa: a phenotypic and phylogenetic analysis.
Nimmo C, Millard J, van Dorp L, Brien K, Moodley S, Wolf A, Grant AD, Padayatchi N, Pym AS, Balloux F, O'Donnell M. Nimmo C, et al. Among authors: pym as. Lancet Microbe. 2020 Aug;1(4):e165-e174. doi: 10.1016/S2666-5247(20)30031-8. Lancet Microbe. 2020. PMID: 32803174 Free PMC article.
Early Detection of Emergent Extensively Drug-Resistant Tuberculosis by Flow Cytometry-Based Phenotyping and Whole-Genome Sequencing.
O'Donnell MR, Larsen MH, Brown TS, Jain P, Munsamy V, Wolf A, Uccellini L, Karim F, de Oliveira T, Mathema B, Jacobs WR, Pym A. O'Donnell MR, et al. Among authors: pym a. Antimicrob Agents Chemother. 2019 Mar 27;63(4):e01834-18. doi: 10.1128/AAC.01834-18. Print 2019 Apr. Antimicrob Agents Chemother. 2019. PMID: 30670422 Free PMC article.
Early versus delayed initiation of highly active antiretroviral therapy for HIV-positive adults with newly diagnosed pulmonary tuberculosis (TB-HAART): a prospective, international, randomised, placebo-controlled trial.
Mfinanga SG, Kirenga BJ, Chanda DM, Mutayoba B, Mthiyane T, Yimer G, Ezechi O, Connolly C, Kapotwe V, Muwonge C, Massaga J, Sinkala E, Kohi W, Lyantumba L, Nyakoojo G, Luwaga H, Doulla B, Mzyece J, Kapata N, Vahedi M, Mwaba P, Egwaga S, Adatu F, Pym A, Joloba M, Rustomjee R, Zumla A, Onyebujoh P. Mfinanga SG, et al. Among authors: pym a. Lancet Infect Dis. 2014 Jul;14(7):563-71. doi: 10.1016/S1473-3099(14)70733-9. Epub 2014 May 5. Lancet Infect Dis. 2014. PMID: 24810491 Clinical Trial.
Test characteristics and potential impact of the urine LAM lateral flow assay in HIV-infected outpatients under investigation for TB and able to self-expectorate sputum for diagnostic testing.
Peter J, Theron G, Chanda D, Clowes P, Rachow A, Lesosky M, Hoelscher M, Mwaba P, Pym A, Dheda K; TB-NEAT team. Peter J, et al. Among authors: pym a. BMC Infect Dis. 2015 Jul 9;15:262. doi: 10.1186/s12879-015-0967-z. BMC Infect Dis. 2015. PMID: 26156025 Free PMC article.
134 results