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Exploiting regulatory heterogeneity to systematically identify enhancers with high accuracy.
Arbel H, Basu S, Fisher WW, Hammonds AS, Wan KH, Park S, Weiszmann R, Booth BW, Keranen SV, Henriquez C, Shams Solari O, Bickel PJ, Biggin MD, Celniker SE, Brown JB. Arbel H, et al. Among authors: brown jb. Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):900-908. doi: 10.1073/pnas.1808833115. Epub 2018 Dec 31. Proc Natl Acad Sci U S A. 2019. PMID: 30598455 Free PMC article.
DNA regions bound at low occupancy by transcription factors do not drive patterned reporter gene expression in Drosophila.
Fisher WW, Li JJ, Hammonds AS, Brown JB, Pfeiffer BD, Weiszmann R, MacArthur S, Thomas S, Stamatoyannopoulos JA, Eisen MB, Bickel PJ, Biggin MD, Celniker SE. Fisher WW, et al. Among authors: brown jb. Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21330-5. doi: 10.1073/pnas.1209589110. Epub 2012 Dec 10. Proc Natl Acad Sci U S A. 2012. PMID: 23236164 Free PMC article.
Genome-wide analysis of promoter architecture in Drosophila melanogaster.
Hoskins RA, Landolin JM, Brown JB, Sandler JE, Takahashi H, Lassmann T, Yu C, Booth BW, Zhang D, Wan KH, Yang L, Boley N, Andrews J, Kaufman TC, Graveley BR, Bickel PJ, Carninci P, Carlson JW, Celniker SE. Hoskins RA, et al. Among authors: brown jb. Genome Res. 2011 Feb;21(2):182-92. doi: 10.1101/gr.112466.110. Epub 2010 Dec 22. Genome Res. 2011. PMID: 21177961 Free PMC article.
Lessons from modENCODE.
Brown JB, Celniker SE. Brown JB, et al. Annu Rev Genomics Hum Genet. 2015;16:31-53. doi: 10.1146/annurev-genom-090413-025448. Epub 2015 Jun 26. Annu Rev Genomics Hum Genet. 2015. PMID: 26133010 Review.
Extensive cross-regulation of post-transcriptional regulatory networks in Drosophila.
Stoiber MH, Olson S, May GE, Duff MO, Manent J, Obar R, Guruharsha KG, Bickel PJ, Artavanis-Tsakonas S, Brown JB, Graveley BR, Celniker SE. Stoiber MH, et al. Among authors: brown jb. Genome Res. 2015 Nov;25(11):1692-702. doi: 10.1101/gr.182675.114. Epub 2015 Aug 20. Genome Res. 2015. PMID: 26294687 Free PMC article.
882 results