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ALS-linked FUS mutations confer loss and gain of function in the nucleus by promoting excessive formation of dysfunctional paraspeckles.
Acta Neuropathol Commun. 2019 Jan 14;7(1):7. doi: 10.1186/s40478-019-0658-x.
Acta Neuropathol Commun. 2019.
PMID: 30642400
Free PMC article.
Antiviral Immune Response as a Trigger of FUS Proteinopathy in Amyotrophic Lateral Sclerosis.
Shelkovnikova TA, An H, Skelt L, Tregoning JS, Humphreys IR, Buchman VL.
Shelkovnikova TA, et al. Among authors: skelt l.
Cell Rep. 2019 Dec 24;29(13):4496-4508.e4. doi: 10.1016/j.celrep.2019.11.094.
Cell Rep. 2019.
PMID: 31875556
Free PMC article.
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